PMID- 20225825
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20100908
LR  - 20100526
IS  - 1520-5827 (Electronic)
IS  - 0743-7463 (Linking)
VI  - 26
IP  - 11
DP  - 2010 Jun 1
TI  - Construction and application of a pH-sensitive nanoreactor via a 
      double-hydrophilic multiarm hyperbranched polymer.
PG  - 8875-81
LID - 10.1021/la9046275 [doi]
AB  - A double-hydrophilic multiarm hyperbranched polymer with a hyperbranched 
      poly(amidoamine) (HPAMAM) core and many poly(ethylene glycol) monomethyl ether 
      (MPEG) arms connected by pH-sensitive acylhydrazone bonds (HPAMAM-g-MPEG) was 
      successfully prepared. Benefiting from the cationic dendritic core and PEGylation 
      shell, the double-hydrophilic multiarm hyperbranched polymer was used as a 
      nanoreactor for CdS quantum dots (CdS QDs) synthesis in aqueous solution. The 
      obtained HPAMAM-g-MPEG and CdS/HPAMAM-g-MPEG nanocomposites were carefully 
      characterized by (1)H NMR, (13)C NMR, Fourier transform infrared spectroscopy 
      (FTIR), ultraviolet-visible absorption spectroscopy (UV-vis), fluorescence 
      spectroscopy (FL), dynamic light scattering (DLS), transmission electron 
      microscopy (TEM), selected area electron diffraction (SAED), and electronic 
      dispersive X-ray spectroscopy (EDS) analysis. Both (1)H NMR and fluorescence 
      spectroscopy investigations confirmed that the acylhydrazone linkage between the 
      dendritic core and linear arms was readily broken under acidic condition (pH 
      <5.5). When MPEG arms departed from the HPAMAM core, the fluorescence intensity 
      of CdS/HPAMAM-g-MPEG nanocomposites greatly increased. Such pH-responsive 
      behavior of CdS/HPAMAM-g-MPEG nanocomposites was utilized as an exploration of a 
      novel fluorescence probe in an acidic lysosome exemplified by COS-7 cells.
FAU - Zhu, Lijuan
AU  - Zhu L
AD  - School of Chemistry and Chemical Engineering, State Key Laboratory of Metal 
      Matrix Composites, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 
      200240, People's Republic of China.
FAU - Shi, Yunfeng
AU  - Shi Y
FAU - Tu, Chunlai
AU  - Tu C
FAU - Wang, Ruibing
AU  - Wang R
FAU - Pang, Yan
AU  - Pang Y
FAU - Qiu, Feng
AU  - Qiu F
FAU - Zhu, Xinyuan
AU  - Zhu X
FAU - Yan, Deyue
AU  - Yan D
FAU - He, Lin
AU  - He L
FAU - Jin, Chengyu
AU  - Jin C
FAU - Zhu, Bangshang
AU  - Zhu B
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Langmuir
JT  - Langmuir : the ACS journal of surfaces and colloids
JID - 9882736
EDAT- 2010/03/17 06:00
MHDA- 2010/03/17 06:01
CRDT- 2010/03/16 06:00
PHST- 2010/03/16 06:00 [entrez]
PHST- 2010/03/17 06:00 [pubmed]
PHST- 2010/03/17 06:01 [medline]
AID - 10.1021/la9046275 [doi]
PST - ppublish
SO  - Langmuir. 2010 Jun 1;26(11):8875-81. doi: 10.1021/la9046275.