PMID- 20226772 OWN - NLM STAT- MEDLINE DCOM- 20100928 LR - 20191210 IS - 1872-6240 (Electronic) IS - 0006-8993 (Linking) VI - 1329 DP - 2010 May 6 TI - Acute high-frequency rTMS of the left dorsolateral prefrontal cortex and attentional control in healthy young men. PG - 152-8 LID - 10.1016/j.brainres.2010.03.013 [doi] AB - Previous studies have shown that high-frequency repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex induces neuromodulation in prefrontal and striatal regions. We hypothesized that high-frequency rTMS over the dorsolateral prefrontal cortex would influence attentional control, which has been associated with neural activity in the same region. Seventeen healthy young men volunteered to participate in a sham-controlled rTMS study. Participants received both rTMS and sham stimulation on separate days and the Conners' continuous performance test was used to assess response inhibition and attentional vigilance. Results indicated that participants showed fewer commission errors during trials after rTMS as compared with sham stimulation, at longer interstimulus intervals (ISIs), which suggests that high-frequency rTMS may have the potential to improve response inhibition. This finding contributes to the understanding of the relationship between the dorsolateral prefrontal cortex and attentional control and suggests possible therapeutic applications for high-frequency rTMS. CI - Copyright 2010 Elsevier B.V. All rights reserved. FAU - Hwang, Ji Hee AU - Hwang JH AD - Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul, Korea. FAU - Kim, Sang Hee AU - Kim SH FAU - Park, Chang Soo AU - Park CS FAU - Bang, Seong Ae AU - Bang SA FAU - Kim, Sang Eun AU - Kim SE LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20100311 PL - Netherlands TA - Brain Res JT - Brain research JID - 0045503 SB - IM MH - Attention/*physiology MH - Brain Mapping/methods MH - Functional Laterality/physiology MH - Humans MH - *Inhibition, Psychological MH - Male MH - Neuropsychological Tests MH - Prefrontal Cortex/*physiology MH - Reaction Time/physiology MH - Reference Values MH - Time Factors MH - *Transcranial Magnetic Stimulation MH - Young Adult EDAT- 2010/03/17 06:00 MHDA- 2010/09/30 06:00 CRDT- 2010/03/16 06:00 PHST- 2009/03/30 00:00 [received] PHST- 2010/02/18 00:00 [revised] PHST- 2010/03/04 00:00 [accepted] PHST- 2010/03/16 06:00 [entrez] PHST- 2010/03/17 06:00 [pubmed] PHST- 2010/09/30 06:00 [medline] AID - S0006-8993(10)00537-8 [pii] AID - 10.1016/j.brainres.2010.03.013 [doi] PST - ppublish SO - Brain Res. 2010 May 6;1329:152-8. doi: 10.1016/j.brainres.2010.03.013. Epub 2010 Mar 11.