PMID- 20233113 OWN - NLM STAT- MEDLINE DCOM- 20100812 LR - 20220317 IS - 1369-1627 (Electronic) IS - 0954-0261 (Linking) VI - 22 IP - 1 DP - 2010 TI - Personality characteristics and disorders in multiple sclerosis patients: assessment and treatment. PG - 43-54 LID - 10.3109/09540261003589349 [doi] AB - Multiple sclerosis (MS) is a major inflammatory and demyelinating disease of the central nervous system. Although a significant incidence and prevalence of psychological disorders in MS has been reported there is limited data on the prevalence of personality disorders (PD) in these patients. Recent findings indicate the need for early diagnosis and treatment of PD in MS patients in the interests of prognosis, conformity to treatment and patient's quality of life improvement. This article summarizes existing evidence on prevalence, types and diagnostic criteria of PD in MS, clinical manifestations of personality pathology or changes in MS patients, and instruments currently used for diagnosis and assessment of PD in this group of patients. Underlying mechanisms suggested as causes of personality changes in MS patients are also discussed. The article reviews therapeutic strategies, including pharmacotherapy and psychotherapy interventions and emphasizes the need for a multidisciplinary approach to patient's treatment. FAU - Stathopoulou, Anastasia AU - Stathopoulou A AD - Department of Psychiatry, University of Patras Medical School, General University Hospital, Rio-Patras, Greece. FAU - Christopoulos, Platon AU - Christopoulos P FAU - Soubasi, Evanthia AU - Soubasi E FAU - Gourzis, Philippos AU - Gourzis P LA - eng PT - Journal Article PT - Review PL - England TA - Int Rev Psychiatry JT - International review of psychiatry (Abingdon, England) JID - 8918131 SB - IM MH - Humans MH - Multiple Sclerosis/complications/epidemiology/*psychology MH - *Personality MH - Personality Disorders/complications/*diagnosis/epidemiology/etiology/*therapy MH - Personality Inventory MH - Prevalence MH - Psychiatric Status Rating Scales MH - Psychotherapy RF - 55 EDAT- 2010/03/18 06:00 MHDA- 2010/08/13 06:00 CRDT- 2010/03/18 06:00 PHST- 2010/03/18 06:00 [entrez] PHST- 2010/03/18 06:00 [pubmed] PHST- 2010/08/13 06:00 [medline] AID - 10.3109/09540261003589349 [doi] PST - ppublish SO - Int Rev Psychiatry. 2010;22(1):43-54. doi: 10.3109/09540261003589349.