PMID- 20297660
OWN - NLM
STAT- MEDLINE
DCOM- 20100427
LR  - 20110124
IS  - 0016-6758 (Print)
IS  - 0016-6758 (Linking)
VI  - 46
IP  - 2
DP  - 2010 Feb
TI  - [Syntropic genes of allergic diseases].
PG  - 255-61
AB  - Common (syntropic) genes of allergic diseases (ADs) HLA-DQB1, HLA-DRB1, IL4, 
      IL4RA, MS4A2, HLA-DQA1, LTC4S, IL13, IL10, and TGFBL have been identified on the 
      basis of information from the HuGENet internet database. The functional sphere of 
      competence of these genes is associated mainly with the initiation and regulation 
      of an immune response and inflammation. Importance of these processes in the 
      development of ADs is underlined. The results of cluster analysis of allergic 
      diseases obtained using the data on common genes predisposing to their 
      development are presented. Genetic clusterization ofADs confirms their accepted 
      clinical classification.
FAU - Freidin, M B
AU  - Freidin MB
FAU - Puzyrev, V P
AU  - Puzyrev VP
LA  - rus
PT  - English Abstract
PT  - Journal Article
PL  - Russia (Federation)
TA  - Genetika
JT  - Genetika
JID - 0047354
RN  - 0 (Cytokines)
RN  - 0 (HLA-D Antigens)
RN  - 0 (IL4R protein, human)
RN  - 0 (Interleukin-4 Receptor alpha Subunit)
RN  - 0 (MS4A2 protein, human)
RN  - 0 (Receptors, IgE)
SB  - IM
EIN - Genetika. 2010 Oct;46(10):1440
MH  - Cytokines/*genetics/immunology
MH  - Female
MH  - HLA-D Antigens/*genetics/immunology
MH  - Humans
MH  - Hypersensitivity/*genetics/immunology
MH  - Interleukin-4 Receptor alpha Subunit/*genetics/immunology
MH  - Male
MH  - Receptors, IgE/*genetics/immunology
EDAT- 2010/03/20 06:00
MHDA- 2010/04/28 06:00
CRDT- 2010/03/20 06:00
PHST- 2010/03/20 06:00 [entrez]
PHST- 2010/03/20 06:00 [pubmed]
PHST- 2010/04/28 06:00 [medline]
PST - ppublish
SO  - Genetika. 2010 Feb;46(2):255-61.