PMID- 20307352
OWN - NLM
STAT- MEDLINE
DCOM- 20100809
LR  - 20100714
IS  - 1475-2662 (Electronic)
IS  - 0007-1145 (Linking)
VI  - 104
IP  - 2
DP  - 2010 Jul
TI  - The influence of maternal glycaemia and dietary glycaemic index on pregnancy 
      outcome in healthy mothers.
PG  - 153-9
LID - 10.1017/S0007114510000425 [doi]
AB  - Infant birth weight has increased in Ireland in recent years along with levels of 
      childhood overweight and obesity. The present article reviews the current 
      literature on maternal glycaemia and the role of the dietary glycaemic index (GI) 
      and its impact on pregnancy outcomes. It is known that maternal weight and weight 
      gain significantly influence infant birth weight. Fetal macrosomia (birth weight 
      >4000 g) is associated with an increased risk of perinatal trauma to both mother 
      and infant. Furthermore, macrosomic infants have greater risk of being obese in 
      childhood, adolescence and adulthood compared to normal-sized infants. There is 
      evidence that there is a direct relationship between maternal blood glucose 
      levels during pregnancy and fetal growth and size at birth, even when maternal 
      blood glucose levels are within their normal range. Thus, maintaining blood 
      glucose concentrations within normal parameters during pregnancy may reduce the 
      incidence of fetal macrosomia. Maternal diet, and particularly its carbohydrate 
      (CHO) type and content, influences maternal blood glucose concentrations. 
      However, different CHO foods produce different glycaemic responses. The GI was 
      conceived by Jenkins in 1981 as a method for assessing the glycaemic responses of 
      different CHO. Data from clinical studies in healthy pregnant women have 
      documented that consuming a low-GI diet during pregnancy reduces peaks in 
      postprandial glucose levels and normalises infant birth weight. Pregnancy is a 
      physiological condition where the GI may be of particular relevance as glucose is 
      the primary fuel for fetal growth.
FAU - McGowan, Ciara A
AU  - McGowan CA
AD  - UCD Obstetrics and Gynaecology, School of Medicine and Medical Science, National 
      Maternity Hospital, University College Dublin, Holles Street, Dublin 2, Republic 
      of Ireland.
FAU - McAuliffe, Fionnuala M
AU  - McAuliffe FM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20100323
PL  - England
TA  - Br J Nutr
JT  - The British journal of nutrition
JID - 0372547
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
SB  - IM
MH  - *Blood Glucose
MH  - Diet
MH  - Dietary Carbohydrates/administration & dosage/classification
MH  - Female
MH  - *Glycemic Index
MH  - Humans
MH  - Infant, Newborn
MH  - Pregnancy/*blood
MH  - Pregnancy Complications/prevention & control
MH  - *Pregnancy Outcome
RF  - 66
EDAT- 2010/03/24 06:00
MHDA- 2010/08/10 06:00
CRDT- 2010/03/24 06:00
PHST- 2010/03/24 06:00 [entrez]
PHST- 2010/03/24 06:00 [pubmed]
PHST- 2010/08/10 06:00 [medline]
AID - S0007114510000425 [pii]
AID - 10.1017/S0007114510000425 [doi]
PST - ppublish
SO  - Br J Nutr. 2010 Jul;104(2):153-9. doi: 10.1017/S0007114510000425. Epub 2010 Mar 
      23.