PMID- 20334930 OWN - NLM STAT- MEDLINE DCOM- 20100622 LR - 20100426 IS - 0165-1781 (Print) IS - 0165-1781 (Linking) VI - 177 IP - 1-2 DP - 2010 May 15 TI - Gender differences in delusional disorder: Evidence from an outpatient sample. PG - 235-9 LID - 10.1016/j.psychres.2010.02.017 [doi] AB - Our objective was to study gender differences in delusional disorder (DD), by comparing potential risk factors, clinical correlates, illness course characteristics, and functionality. The sample was composed of 86 outpatients with DD (according to the SCID-I for DSM-IV criteria). The following assessment instruments were used service use and demographic questionnaires, Standardized Assessment of Personality (SAP), the Positive and Negative Symptom Scale (PANSS), Montgomery-Asberg Depression Rating Scale (MADRS), Mini-Mental State Examination (MMSE), Mini International Neuropsychiatry Interview (MINI), Sheehan Disability Inventory (SDI), and the Global Assessment of Functioning (GAF) scale. The female-to-male ratio was 1.6:1. Men were more likely to be single, while women were more likely to be widows. Men had a greater frequency of schizoid and schizotypal premorbid personality disorders and of premorbid substance abuse. There were no differences for other risk factors (immigration, deafness, late onset, other personality disorders, and family history). Men were younger at onset and more frequently had acute onset of the disorder. Men had more severe symptoms (higher score on the global or separate PANSS scales). There were no gender differences for the remaining symptomatological variables (types of DD, presence and severity of depression, presence of hallucinations, severity of global cognitive functioning and presence of axis I comorbidity). Global and partial (work, family, and social) functioning was significantly poorer among men. Course type and consumption of resources appeared to be similar. We conclude that men with DD had significantly more severe symptoms and worse functionality. They also had a higher frequency of schizoid and schizotypal premorbid personality disorders and premorbid substance abuse. CI - Copyright 2010 Elsevier Ireland Ltd. All rights reserved. FAU - de Portugal, Enrique AU - de Portugal E AD - Department of Psychiatry, Hospital Gregorio Maranon, Madrid, Spain. FAU - Gonzalez, Nieves AU - Gonzalez N FAU - Miriam, Vilaplana AU - Miriam V FAU - Haro, Josep M AU - Haro JM FAU - Usall, Judit AU - Usall J FAU - Cervilla, Jorge A AU - Cervilla JA LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20100323 PL - Ireland TA - Psychiatry Res JT - Psychiatry research JID - 7911385 SB - IM MH - Adult MH - Age Factors MH - Aged MH - Female MH - Humans MH - Male MH - Middle Aged MH - Neuropsychological Tests MH - Outpatients/statistics & numerical data MH - Personality Inventory MH - Psychiatric Status Rating Scales MH - Risk Factors MH - Schizophrenia, Paranoid/*epidemiology/*etiology MH - *Sex Characteristics MH - Sex Factors MH - Statistics as Topic EDAT- 2010/03/26 06:00 MHDA- 2010/06/23 06:00 CRDT- 2010/03/26 06:00 PHST- 2009/05/27 00:00 [received] PHST- 2009/11/21 00:00 [revised] PHST- 2010/02/22 00:00 [accepted] PHST- 2010/03/26 06:00 [entrez] PHST- 2010/03/26 06:00 [pubmed] PHST- 2010/06/23 06:00 [medline] AID - S0165-1781(10)00063-6 [pii] AID - 10.1016/j.psychres.2010.02.017 [doi] PST - ppublish SO - Psychiatry Res. 2010 May 15;177(1-2):235-9. doi: 10.1016/j.psychres.2010.02.017. Epub 2010 Mar 23.