PMID- 20339971 OWN - NLM STAT- MEDLINE DCOM- 20100610 LR - 20211020 IS - 1615-2573 (Electronic) IS - 0910-8327 (Linking) VI - 25 IP - 2 DP - 2010 Mar TI - Novel application of black-blood echo-planar imaging to the assessment of myocardial infarction. PG - 104-12 LID - 10.1007/s00380-009-1172-z [doi] AB - The purpose of this study was to clarify the characteristics of black-blood echo-planar imaging (BB-EPI) in the assessment of infarct-related myocardial edema (IRME), compared with T2-weighted imaging (T2WI). Thirteen acute myocardial infarction (MI) patients after reperfusion and 11 old MI patients underwent BB-EPI and T2WI, excluding those with posterior MI. In acute MI patients, signal intensity ratio (SI ratio) of edema to normal myocardium was measured. Black-blood echo-planar imaging revealed hyperintensity in the same region identified as IRME on T2WI in all acute MI patients, and SI ratio was significantly higher in BB-EPI (2.66 +/- 1.58) than in T2WI (1.44 +/- 0.22) (P < 0.05). However, BB-EPI showed hyperintensity in posterior wall, where there is no clinical evidence of acute MI, in 2 out of 13 acute MI patients. Both T2WI and BB-EPI detected no IRME in known old infarct area of all old MI patients, but BB-EPI showed hyperintensity in the posterior wall of 4 out of 11 old MI patients. Black-blood echo-planar imaging can depict IRME with sufficient suppression of background and blood flow signals, and with excellent edema-to-normal myocardium contrast resolution. However, BB-EPI sometimes shows an inconsistent signal area with T2WI specifically in posterior wall. The wide practical use of BB-EPI requires the solution to this serious problem. FAU - Okayama, Satoshi AU - Okayama S AD - First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan. FAU - Uemura, Shiro AU - Uemura S FAU - Watanabe, Makoto AU - Watanabe M FAU - Morikawa, Yoshinobu AU - Morikawa Y FAU - Onoue, Kenji AU - Onoue K FAU - Soeda, Tsunenari AU - Soeda T FAU - Iwama, Hajime AU - Iwama H FAU - Somekawa, Satoshi AU - Somekawa S FAU - Takeda, Yukiji AU - Takeda Y FAU - Uramoto, Hiroki AU - Uramoto H FAU - Kobayashi, Yoshiyuki AU - Kobayashi Y FAU - Saito, Yoshihiko AU - Saito Y LA - eng PT - Comparative Study PT - Journal Article DEP - 20100326 PL - Japan TA - Heart Vessels JT - Heart and vessels JID - 8511258 RN - 0 (Contrast Media) RN - K2I13DR72L (Gadolinium DTPA) SB - IM MH - Aged MH - Aged, 80 and over MH - Contrast Media MH - *Diffusion Magnetic Resonance Imaging MH - Edema, Cardiac/*diagnosis/etiology/pathology MH - Gadolinium DTPA MH - Humans MH - *Magnetic Resonance Imaging, Cine MH - Male MH - Middle Aged MH - Myocardial Infarction/complications/*diagnosis/pathology/therapy MH - Myocardial Perfusion Imaging MH - Myocardium/*pathology MH - Predictive Value of Tests EDAT- 2010/03/27 06:00 MHDA- 2010/06/11 06:00 CRDT- 2010/03/27 06:00 PHST- 2008/11/06 00:00 [received] PHST- 2009/04/30 00:00 [accepted] PHST- 2010/03/27 06:00 [entrez] PHST- 2010/03/27 06:00 [pubmed] PHST- 2010/06/11 06:00 [medline] AID - 10.1007/s00380-009-1172-z [doi] PST - ppublish SO - Heart Vessels. 2010 Mar;25(2):104-12. doi: 10.1007/s00380-009-1172-z. Epub 2010 Mar 26.