PMID- 20353887
OWN - NLM
STAT- MEDLINE
DCOM- 20100819
LR  - 20131121
IS  - 1873-4235 (Electronic)
IS  - 0956-5663 (Linking)
VI  - 25
IP  - 10
DP  - 2010 Jun 15
TI  - Multilayer silver nanoparticles-modified optical fiber tip for high performance 
      SERS remote sensing.
PG  - 2270-5
LID - 10.1016/j.bios.2010.03.007 [doi]
AB  - This work presents the construction and optimization of nanoparticles-modified 
      optical fiber tip (NPs-MOFT) devices for remote sensing by surface-enhanced Raman 
      scattering (SERS). Silver nanoparticles (Ag-NPs) were self-assembled on optical 
      fiber tips through a "layer-by-layer" procedure. It is shown that the SERS 
      performance is at optimum when 5 "layers" of 50 nm Ag-NPs were deposited on the 
      optical fiber tip. Using the optimized Ag-NPs-MOFT device, it was possible to 
      detect 200 nM of the R6G dye in remote sensing mode (backscattering through the 
      fiber). It was also possible to detect dye molecules with different structures 
      and charges at the micro-molar concentration level, including anions, cations and 
      neutral species. It can be envisioned that the Ag-NPs-MOFT device reported in 
      this work can be further developed for SERS-based remote biosensing.
CI  - Copyright 2010 Elsevier B.V. All rights reserved.
FAU - Andrade, Gustavo F S
AU  - Andrade GF
AD  - Department of Chemistry, University of Victoria, PO Box 3055, Victoria, BC, 
      Canada V8W 3V6.
FAU - Fan, MeiKun
AU  - Fan M
FAU - Brolo, Alexandre G
AU  - Brolo AG
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20100310
PL  - England
TA  - Biosens Bioelectron
JT  - Biosensors & bioelectronics
JID - 9001289
RN  - 3M4G523W1G (Silver)
SB  - IM
MH  - Biosensing Techniques/*instrumentation
MH  - Equipment Design
MH  - Equipment Failure Analysis
MH  - Fiber Optic Technology/*instrumentation
MH  - Light
MH  - Nanoparticles/*chemistry/ultrastructure
MH  - Reproducibility of Results
MH  - Scattering, Radiation
MH  - Sensitivity and Specificity
MH  - Silver/*chemistry
MH  - Surface Plasmon Resonance/*instrumentation
EDAT- 2010/04/01 06:00
MHDA- 2010/08/20 06:00
CRDT- 2010/04/01 06:00
PHST- 2009/11/17 00:00 [received]
PHST- 2010/02/15 00:00 [revised]
PHST- 2010/03/03 00:00 [accepted]
PHST- 2010/04/01 06:00 [entrez]
PHST- 2010/04/01 06:00 [pubmed]
PHST- 2010/08/20 06:00 [medline]
AID - S0956-5663(10)00125-9 [pii]
AID - 10.1016/j.bios.2010.03.007 [doi]
PST - ppublish
SO  - Biosens Bioelectron. 2010 Jun 15;25(10):2270-5. doi: 10.1016/j.bios.2010.03.007. 
      Epub 2010 Mar 10.