PMID- 2035516
OWN - NLM
STAT- MEDLINE
DCOM- 19910625
LR  - 20190510
IS  - 0002-9262 (Print)
IS  - 0002-9262 (Linking)
VI  - 133
IP  - 11
DP  - 1991 Jun 1
TI  - Human T-lymphotropic virus type I (HTLV-I) seroprevalence in Jamaica. II. 
      Geographic and ecologic determinants.
PG  - 1125-34
AB  - An island-wide cohort of 13,260 Jamaicans who applied for food-handling licenses 
      during 1985 and 1986 were tested for antibodies to human T-cell lymphotropic 
      virus type I (HTLV-I). Demographic and residence history data were linked to 
      geographic and ecologic measures of elevation, rainfall, crop-growing areas, 
      population density, and additional measures of urbanization and correlated with 
      HTLV-I antibody status. By logistic regression analysis (performed separately for 
      men and women), men and women who currently resided at low elevation (less than 
      or equal to 1,000 ft (305 m)) were more likely to be HTLV-I infected than were 
      those residing at high elevation. Men, but not women, who were born in 
      citrus-growing areas were more likely to be HTLV-I infected than were men who 
      were born in other areas. By univariate analysis, there was a significant 
      positive trend of increasing HTLV-I seroprevalence with increasing amount of 
      annual rainfall associated with birthplace and primary residence areas. However, 
      these associations did not remain significant after adjusting for age and sex. 
      These environmental associations raise the possibility of new modes of viral 
      transmission or host response to infection, although they may simply be 
      surrogates for socioeconomic status, breastfeeding habits, or sexual behavior, 
      which are known determinants of HTLV-I zero prevalence.
FAU - Maloney, E M
AU  - Maloney EM
AD  - Viral Epidemiology Section, National Cancer Institute, Bethesda, MD.
FAU - Murphy, E L
AU  - Murphy EL
FAU - Figueroa, J P
AU  - Figueroa JP
FAU - Gibbs, W N
AU  - Gibbs WN
FAU - Cranston, B
AU  - Cranston B
FAU - Hanchard, B
AU  - Hanchard B
FAU - Holding-Cobham, M
AU  - Holding-Cobham M
FAU - Malley, K
AU  - Malley K
FAU - Blattner, W A
AU  - Blattner WA
LA  - eng
GR  - N01-CP-31006/CP/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Am J Epidemiol
JT  - American journal of epidemiology
JID - 7910653
RN  - 0 (HTLV-I Antibodies)
SB  - IM
CIN - Am J Epidemiol. 1992 Mar 1;135(5):591. PMID: 1570828
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Altitude
MH  - Child
MH  - Ecology
MH  - Female
MH  - HTLV-I Antibodies/*analysis
MH  - HTLV-I Infections/epidemiology/immunology
MH  - Human T-lymphotropic virus 1/immunology/*isolation & purification
MH  - Humans
MH  - Jamaica/epidemiology
MH  - Male
MH  - Middle Aged
MH  - *Population Density
MH  - Rain
MH  - Regression Analysis
EDAT- 1991/06/01 00:00
MHDA- 1991/06/01 00:01
CRDT- 1991/06/01 00:00
PHST- 1991/06/01 00:00 [pubmed]
PHST- 1991/06/01 00:01 [medline]
PHST- 1991/06/01 00:00 [entrez]
AID - 10.1093/oxfordjournals.aje.a115825 [doi]
PST - ppublish
SO  - Am J Epidemiol. 1991 Jun 1;133(11):1125-34. doi: 
      10.1093/oxfordjournals.aje.a115825.