PMID- 20357426
OWN - NLM
STAT- MEDLINE
DCOM- 20110603
LR  - 20140730
IS  - 1423-0356 (Electronic)
IS  - 0025-7931 (Linking)
VI  - 81
IP  - 2
DP  - 2011
TI  - Estimating peak work rate during incremental cycle ergometry from the 6-minute 
      walk distance: differences between reference equations.
PG  - 124-8
LID - 10.1159/000308464 [doi]
AB  - BACKGROUND: Prescription of an appropriate exercise training intensity is 
      critical to optimise the outcomes of pulmonary rehabilitation; however, 
      prescribing cycle ergometry training is challenging if peak work is unknown. 
      Recently two studies reported regression equations which allow estimation of peak 
      cycle work rate from the 6-minute walk distance (6MWD) in chronic obstructive 
      pulmonary disease (COPD). OBJECTIVES: To compare estimates of peak work and 
      target training work rate (60% peak) obtained from these equations. METHODS: 
      Sixty-four (38 male) subjects, mean +/- SD age 70 +/- 8 years and FEV(1) 49 +/- 18% 
      predicted with COPD performed the 6-minute walk test according to a standardised 
      protocol. Estimates of peak work were obtained using the published equations and 
      agreement was examined using Bland and Altman plots. RESULTS: Mean 6MWD was 376 +/- 
      86 m compared to 464 +/- 110 m and 501 +/- 83 m in samples used to derive the 
      equations. There was substantial variation in estimates of peak work between 
      equations (range 1-75 Watts difference) with a coefficient of variation of 35%. 
      Differences were greater in men than in women (p < 0.001). The Luxton equation 
      predicted higher peak work than the Hill equation in younger subjects and at work 
      rates over 50 Watts. Estimated training work rate differed by more than 20 Watts 
      in 18 subjects (28%). CONCLUSIONS: This comparison of reference equations for 
      predicting peak cycle work rate from 6MWD indicates substantial variation between 
      methods that differs systematically across the range of work rates. Further 
      research is required to validate the equations and assess their utility for 
      exercise prescription in pulmonary rehabilitation.
CI  - Copyright (c) 2010 S. Karger AG, Basel.
FAU - Holland, A E
AU  - Holland AE
AD  - School of Physiotherapy, La Trobe University, Melbourne, Vic., Australia. 
      a.holland@alfred.org.au
FAU - Hill, K
AU  - Hill K
FAU - Alison, J A
AU  - Alison JA
FAU - Luxton, N
AU  - Luxton N
FAU - Mackey, M G
AU  - Mackey MG
FAU - Hill, C J
AU  - Hill CJ
FAU - Jenkins, S C
AU  - Jenkins SC
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20100401
PL  - Switzerland
TA  - Respiration
JT  - Respiration; international review of thoracic diseases
JID - 0137356
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Algorithms
MH  - Exercise/*physiology
MH  - *Exercise Test
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Physical Exertion
EDAT- 2010/04/02 06:00
MHDA- 2011/06/04 06:00
CRDT- 2010/04/02 06:00
PHST- 2009/10/22 00:00 [received]
PHST- 2010/02/01 00:00 [accepted]
PHST- 2010/04/02 06:00 [entrez]
PHST- 2010/04/02 06:00 [pubmed]
PHST- 2011/06/04 06:00 [medline]
AID - 000308464 [pii]
AID - 10.1159/000308464 [doi]
PST - ppublish
SO  - Respiration. 2011;81(2):124-8. doi: 10.1159/000308464. Epub 2010 Apr 1.