PMID- 20367816
OWN - NLM
STAT- MEDLINE
DCOM- 20100706
LR  - 20191210
IS  - 1365-2753 (Electronic)
IS  - 1356-1294 (Linking)
VI  - 16
IP  - 1
DP  - 2010 Feb
TI  - Psychometric re-evaluation of the immunosuppressant therapy adherence scale among 
      solid-organ transplant recipients.
PG  - 64-8
LID - 10.1111/j.1365-2753.2008.01115.x [doi]
AB  - RATIONALE: The objective of this study was to conduct a psychometric 
      re-evaluation of the immunosuppressant therapy adherence scale (ITAS), a 
      self-report measure of immunosuppressant therapy (IST) adherence targeted to 
      solid-organ transplant recipients. METHODS: Mailed questionnaires were used to 
      collect data from 141 transplant recipients. A factor analysis of the ITAS was 
      conducted. Validity was examined via Pearson's product-moment correlations (r) to 
      theoretically tied measures of social support and resilience. Cronbach's and 
      split-half alpha coefficients determined internal consistency. RESULTS: The 
      response rate was 72.3%. The aggregate mean on ITAS' summed scores was 11.0 
      (standard deviation = 1.7). The single IST adherence factor had an eigenvalue of 
      2.92 and accounted for 73% of the scale items' variance. Component loadings for 
      ITAS items were high (> or = 0.80). Zero-order correlations among scale items 
      were moderately strong (> or = 0.57) and significant (P < 0.01). ITAS summed 
      scores were significantly associated with measures of social support and 
      resilience (r > or = 0.20, P < 0.05). Cronbach's alpha was 0.87. The Guttman 
      split-half coefficient was 0.90. CONCLUSIONS: This re-evaluation provides needed 
      confirmation that the ITAS is a valid and reliable measure of IST adherence. The 
      ITAS may be useful as an IST adherence measure in the outpatient transplant 
      clinic setting as it is easy to administer, brief and less expensive than many 
      other adherence measures.
FAU - Wilks, Scott E
AU  - Wilks SE
AD  - Louisiana State University, School of Social Work, Baton Rouge, LA, USA.
FAU - Spivey, Christina A
AU  - Spivey CA
FAU - Chisholm-Burns, Marie A
AU  - Chisholm-Burns MA
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Validation Study
PL  - England
TA  - J Eval Clin Pract
JT  - Journal of evaluation in clinical practice
JID - 9609066
RN  - 0 (Immunosuppressive Agents)
SB  - IM
MH  - Cross-Sectional Studies
MH  - Factor Analysis, Statistical
MH  - Female
MH  - Humans
MH  - *Immunosuppressive Agents
MH  - Male
MH  - *Medication Adherence
MH  - Middle Aged
MH  - *Organ Transplantation
MH  - Principal Component Analysis
MH  - Psychometrics
MH  - Reproducibility of Results
MH  - Resilience, Psychological
MH  - Social Support
MH  - *Surveys and Questionnaires
EDAT- 2010/04/07 06:00
MHDA- 2010/07/07 06:00
CRDT- 2010/04/07 06:00
PHST- 2010/04/07 06:00 [entrez]
PHST- 2010/04/07 06:00 [pubmed]
PHST- 2010/07/07 06:00 [medline]
AID - JEP1115 [pii]
AID - 10.1111/j.1365-2753.2008.01115.x [doi]
PST - ppublish
SO  - J Eval Clin Pract. 2010 Feb;16(1):64-8. doi: 10.1111/j.1365-2753.2008.01115.x.