PMID- 20370600 OWN - NLM STAT- MEDLINE DCOM- 20101202 LR - 20220408 IS - 1538-2443 (Electronic) IS - 1355-0284 (Linking) VI - 16 IP - 2 DP - 2010 Mar TI - Human immunodeficiency virus-associated cytomegalovirus infection with multiple small vessel cerebral infarcts in the setting of early immune reconstitution. PG - 179-84 LID - 10.3109/13550281003735717 [doi] AB - Cytomegalovirus (CMV) infection is an important cause of neurologic disease in the context of advanced human immunodeficiency virus (HIV) infection and is recognized as a cause of immune reconstitution inflammatory syndrome (IRIS) after initiation of highly active antiretroviral therapy (HAART). Central nervous system vasculitis secondary to CMV has only rarely been described in the context of HIV, despite the established ability of CMV to infect microvascular endothelial cells in the brain. However, we report a case that demonstrates the association between CMV and multiple small vessel cerebral infarct lesions after initiation of HAART. FAU - Anderson, Albert M AU - Anderson AM AD - Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA. aande2@emory.edu FAU - Fountain, Jack A AU - Fountain JA FAU - Green, Sonya B AU - Green SB FAU - Bloom, Sharon A AU - Bloom SA FAU - Palmore, Melody P AU - Palmore MP LA - eng PT - Journal Article PL - United States TA - J Neurovirol JT - Journal of neurovirology JID - 9508123 RN - 0 (Antiviral Agents) SB - IM MH - Adult MH - Antiretroviral Therapy, Highly Active MH - Antiviral Agents/therapeutic use MH - Cerebral Infarction/physiopathology/*virology MH - Cytomegalovirus Retinitis/*complications/drug therapy/physiopathology MH - HIV Infections/*complications/drug therapy/physiopathology MH - Humans MH - Immune Reconstitution Inflammatory Syndrome/physiopathology/*virology MH - Magnetic Resonance Imaging MH - Male MH - Vasculitis, Central Nervous System/physiopathology/virology EDAT- 2010/04/08 06:00 MHDA- 2010/12/14 06:00 CRDT- 2010/04/08 06:00 PHST- 2010/04/08 06:00 [entrez] PHST- 2010/04/08 06:00 [pubmed] PHST- 2010/12/14 06:00 [medline] AID - 10.3109/13550281003735717 [doi] PST - ppublish SO - J Neurovirol. 2010 Mar;16(2):179-84. doi: 10.3109/13550281003735717.