PMID- 20376233
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20211020
IS  - 0975-1580 (Electronic)
IS  - 0972-124X (Print)
IS  - 0972-124X (Linking)
VI  - 13
IP  - 1
DP  - 2009 Jan
TI  - Effect of periodontal therapy on hemoglobin and erythrocyte levels in chronic 
      generalized periodontitis patients: An interventional study.
PG  - 6-11
LID - 10.4103/0972-124X.51887 [doi]
AB  - AIMS AND OBJECTIVES: Anemia of chronic disease (ACD) is one of the most common 
      forms of anemia. It is defined as anemia occurring in chronic infections, 
      inflammatory conditions or neoplastic disorders which are not due to marrow 
      deficiencies or other diseases, and occurring despite the presence of adequate 
      iron stores and vitamins. Periodontitis is one of the most prevalent chronic 
      inflammatory diseases in humans. This study aimed at finding out if 
      periodontitis, like other inflammatory conditions, could lead to anemia. 
      MATERIALS AND METHODS: Thirty chronic generalized periodontitis male patients 
      with hemoglobin levels below 15 mg/dl and serum ferritin values above 30 ng/ml 
      were selected. The various blood parameters recorded at baseline were hemoglobin 
      levels(Hb), erythrocyte count (RBC), erythrocyte sedimentation rate (ESR), mean 
      corpuscular volume(MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular 
      hemoglobin concentration (MCHC). PERIODONTAL PARAMETERS RECORDED AT BASELINE 
      INCLUDED: plaque index, gingival index, probing pocket depth, clinical attachment 
      level. Periodontal treatment including surgery if required was carried out in all 
      the patients. Periodontal status of patients was monitored by repeating 
      evaluation of periodontal indices at three months and at the end of one year. The 
      hematological values were again measured at the end of one year. RESULTS: The 
      results showed that correction of periodontal inflammation resulted in a 
      significant increase in hemoglobin levels and erythrocyte counts. The erythrocyte 
      sedimentation rate showed a reduction indicating resolution of periodontal 
      inflammation. There was a significant, but much lesser, improvement in MCV, MCH 
      and MCHC values. CONCLUSION: The results of this study showed that treatment of 
      periodontitis leads to an improvement in hematocrit and other related blood 
      parameters in chronic generalized periodontitis patients with anemia. This 
      provides evidence that periodontitis like other chronic diseases may also cause 
      anemia.
FAU - Agarwal, Nupur
AU  - Agarwal N
AD  - PG Student, Department of Periodontics, J.S.S. Dental College & Hospital, Mysore, 
      India.
FAU - Kumar, Veerendra S C
AU  - Kumar VS
FAU - Gujjari, Sheela A
AU  - Gujjari SA
LA  - eng
PT  - Journal Article
PL  - India
TA  - J Indian Soc Periodontol
JT  - Journal of Indian Society of Periodontology
JID - 101499342
PMC - PMC2846680
OTO - NOTNLM
OT  - ACD
OT  - anemia
OT  - hemoglobin
OT  - periodontitis
COIS- Conflict of Interest: None declared.
EDAT- 2009/01/01 00:00
MHDA- 2009/01/01 00:01
PMCR- 2009/01/01
CRDT- 2010/04/09 06:00
PHST- 2008/12/12 00:00 [received]
PHST- 2009/04/11 00:00 [accepted]
PHST- 2010/04/09 06:00 [entrez]
PHST- 2009/01/01 00:00 [pubmed]
PHST- 2009/01/01 00:01 [medline]
PHST- 2009/01/01 00:00 [pmc-release]
AID - JISP-13-6 [pii]
AID - 10.4103/0972-124X.51887 [doi]
PST - ppublish
SO  - J Indian Soc Periodontol. 2009 Jan;13(1):6-11. doi: 10.4103/0972-124X.51887.