PMID- 20378233
OWN - NLM
STAT- MEDLINE
DCOM- 20101028
LR  - 20100517
IS  - 1579-2129 (Electronic)
IS  - 0300-2896 (Linking)
VI  - 46
IP  - 5
DP  - 2010 May
TI  - [Use of positron emission tomography in assessing hidden extrathoracic metastasis 
      in non small cell lung cancer].
PG  - 238-43
LID - 10.1016/j.arbres.2010.02.003 [doi]
AB  - INTRODUCTION: Positron emission tomography combined with computed axial 
      tomography (PET/CT) is used for staging non small cell lung cancer (NSCLC). This 
      study aims to describe PET/CT findings of unsuspected extrathoracic metastasis 
      when used in mediastinal evaluation of patients with apparently resectable NSCLC. 
      PATIENTS AND METHOD: Prospective and concurrent study including all NSCLC 
      patients between June 2004 and November 2006 who underwent PET/CT after 
      considering them as candidates for surgery, with resectable disease after 
      bronchoscopy, thorax and abdominal CT, brain CT and bone gammagraphy evaluation, 
      if metastasis at these locations were suspected. Metastasis were confirmed 
      histopathologically or assumed when they had a compatible evolution. RESULTS: A 
      total of 91 patients with NSCLC underwent PET/CT. In 24 of them (26%) at least 
      one suspicious extrathoracic uptake was seen. In 7 patients (7.7%) those uptakes 
      were NSCLC extrathoracic metastasis hidden from conventional staging. In 3 of 
      these cases (13.1%) extrathoracic uptakes corresponded to metacrhonous tumours or 
      pre-malignant conditions. Benign lesions were found in 12 patients (13.1%), and 
      in 2 cases (2.2%) the uptake origins were undetermined. CONCLUSIONS: PET/CT is a 
      complementary diagnosis method for assessing hidden metastases which could modify 
      the therapeutical approach in patients otherwise suitable for surgery.
CI  - Copyright 2009 SEPAR. Published by Elsevier Espana. All rights reserved.
FAU - Alonso Moralejo, Rodrigo
AU  - Alonso Moralejo R
AD  - Servicio de Neumologia, Hospital Universitario 12 de Octubre, Madrid, Espana. 
      ralonsomoralejo@gmail.com
FAU - Sayas Catalan, Javier
AU  - Sayas Catalan J
FAU - Garcia Lujan, Ricardo
AU  - Garcia Lujan R
FAU - Coronado Poggio, Monica
AU  - Coronado Poggio M
FAU - Monso Molas, Eduard
AU  - Monso Molas E
FAU - Lopez Encuentra, Angel
AU  - Lopez Encuentra A
LA  - spa
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
TT  - Utilidad de la tomografia por emision de positrones en la deteccion de metastasis 
      ocultas extratoracicas en el carcinoma broncogenico no celulas pequenas.
DEP - 20100407
PL  - Spain
TA  - Arch Bronconeumol
JT  - Archivos de bronconeumologia
JID - 0354720
SB  - IM
MH  - Aged
MH  - Carcinoma, Non-Small-Cell Lung/*diagnosis/*secondary
MH  - Female
MH  - Humans
MH  - Lung Neoplasms/*pathology
MH  - Male
MH  - *Positron-Emission Tomography
MH  - Prospective Studies
MH  - *Tomography, X-Ray Computed
EDAT- 2010/04/10 06:00
MHDA- 2010/10/29 06:00
CRDT- 2010/04/10 06:00
PHST- 2009/09/23 00:00 [received]
PHST- 2010/02/08 00:00 [revised]
PHST- 2010/02/11 00:00 [accepted]
PHST- 2010/04/10 06:00 [entrez]
PHST- 2010/04/10 06:00 [pubmed]
PHST- 2010/10/29 06:00 [medline]
AID - S0300-2896(10)00052-9 [pii]
AID - 10.1016/j.arbres.2010.02.003 [doi]
PST - ppublish
SO  - Arch Bronconeumol. 2010 May;46(5):238-43. doi: 10.1016/j.arbres.2010.02.003. Epub 
      2010 Apr 7.