PMID- 20386087
OWN - NLM
STAT- MEDLINE
DCOM- 20110531
LR  - 20211020
IS  - 1720-8386 (Electronic)
IS  - 0391-4097 (Linking)
VI  - 33
IP  - 10
DP  - 2010 Nov
TI  - Subepicardial adipose tissue thickness and its relation with anthropometric and 
      clinical parameters in pubertal obese children.
PG  - 715-9
AB  - AIM: To determine the relation of echocardiographic subepicardial adipose tissue 
      (SAT) thickness with anthropometric and clinical parameters in pubertal obese 
      children. SUBJECTS AND METHODS: A total of 52 obese pubertal subjects (13.1+/-1.56 
      yr, 27 male patients) and 39 age- and gender-matched lean pubertal subjects 
      (13.0+/-1.28 yr, 16 male patients) were included in the study. Serum glucose, lipid 
      profile, and insulin levels were measured during the fasting state. Each subject 
      underwent a transthoracic echocardiography and the SAT thickness was measured 
      during end-diastole from the parasternal long-axis views. RESULTS: The obese 
      pubertal subjects had significantly higher SAT, triceps skin fold (TSF) thickness 
      (mm), waist (WC) and mid-arm circumference (MAC) values (cm) compared with lean 
      pubertal subjects group (p<0.05). Correlation analysis showed that SAT thickness 
      was significantly related with age, SD score-body mass index (SDS-BMI), BMI, WC, 
      MAC, TSF, and homeostasis model assessment of insulin resistance (HOMA-IR) 
      (p<0.05), whereas there was no significant relation of SAT with hip circumference 
      and waist to hip ratio (p>0.05). As an optimal cut-off point, a SAT thickness of 
      5.25 mm determined IR with 92% sensitivity and 62.1% specificity. CONCLUSIONS: 
      Our study showed that SAT thickness in obese pubertal children shows a good 
      correlation with age, SDS-BMI, BMI, WC, MAC, TSF, and HOMA-IR. In addition, our 
      results suggest that SAT thickness might be used as a supportive data for risk 
      stratification of metabolic syndrome in obese children.
FAU - Abaci, A
AU  - Abaci A
AD  - Division of Pediatric Endocrinology, Kecioren Training and Research Hospital, 
      Ankara, Turkey. ayhanabaci@gmail.com
FAU - Ozdemir, O
AU  - Ozdemir O
FAU - Hizli, S
AU  - Hizli S
FAU - Razi, C Hasan
AU  - Razi CH
FAU - Kabakus, N
AU  - Kabakus N
LA  - eng
PT  - Journal Article
DEP - 20100412
PL  - Italy
TA  - J Endocrinol Invest
JT  - Journal of endocrinological investigation
JID - 7806594
SB  - IM
MH  - Adipose Tissue/*pathology
MH  - Adolescent
MH  - Anthropometry
MH  - Body Mass Index
MH  - Case-Control Studies
MH  - Child
MH  - Echocardiography
MH  - Female
MH  - Humans
MH  - Insulin Resistance/physiology
MH  - Male
MH  - Obesity/diagnostic imaging/*pathology/physiopathology
MH  - Organ Size
MH  - Pericardium
MH  - *Puberty/physiology
MH  - Thinness/diagnostic imaging/pathology/physiopathology
EDAT- 2010/04/14 06:00
MHDA- 2011/06/01 06:00
CRDT- 2010/04/14 06:00
PHST- 2010/04/14 06:00 [entrez]
PHST- 2010/04/14 06:00 [pubmed]
PHST- 2011/06/01 06:00 [medline]
AID - 6972 [pii]
AID - 10.1007/BF03346676 [doi]
PST - ppublish
SO  - J Endocrinol Invest. 2010 Nov;33(10):715-9. doi: 10.1007/BF03346676. Epub 2010 
      Apr 12.