PMID- 20395881
OWN - NLM
STAT- MEDLINE
DCOM- 20110204
LR  - 20220408
IS  - 1528-1159 (Electronic)
IS  - 0362-2436 (Linking)
VI  - 35
IP  - 23
DP  - 2010 Nov 1
TI  - The minimum clinically important difference in Scoliosis Research Society-22 
      Appearance, Activity, And Pain domains after surgical correction of adolescent 
      idiopathic scoliosis.
PG  - 2079-83
LID - 10.1097/BRS.0b013e3181c61fd7 [doi]
AB  - STUDY DESIGN: Longitudinal cohort. OBJECTIVE: To determine the minimum clinically 
      important difference (MCID) of the Scoliosis Research Society (SRS)-22 
      Appearance, Activity, and Pain domains in patients with adolescent idiopathic 
      scoliosis undergoing surgical correction of their spinal deformity. SUMMARY OF 
      BACKGROUND DATA: The MCID, a threshold of improvement that is clinically relevant 
      to the individual patient, is increasingly used to evaluate treatment 
      effectiveness. MCID values for the SRS-22 domains have not been determined. 
      METHODS: Patients with adolescent idiopathic scoliosis who underwent surgical 
      correction and had completed SRS-22 before operation and the SRS-30 and Scoliosis 
      Appearance Questionnaire (SAQ) at 1 year after operation from a multicenter 
      database for pediatric scoliosis were identified. The SAQ is a modification of 
      the Walter Reed Visual Assessment Scale and is used to assess the patient's 
      perception of their spinal deformity. Paired sample t tests were used to compare 
      preoperative and 1-year postoperative scores. Spearman correlations were used to 
      evaluate associations between domain scores and summed responses to anchors for 
      Appearance, Activity, and Pain. MCID values for the SRS-22 domains were 
      determined using receiver operating characteristic curve analysis, with summed 
      responses to anchor questions 23 to 30 of the SRS-30 and items 26 and 32 of the 
      SAQ. RESULTS: There were 735 women and 152 men with a mean age of 14.3 years and 
      a mean Cobb angle of 53 degrees . There was a statistically significant difference 
      between paired preoperative and 1-year SRS domain scores. Analysis of variance 
      showed a statistically significant difference between the summed responses to the 
      anchors. The MCID was 0.20 for the Pain domain (area under the curve [AUC] = 
      0.723), 0.08 for Activity (AUC = 0.648), and 0.98 for Appearance (AUC = 0.629). 
      The MCID for activity was less than the standard error of measurement. 
      CONCLUSION: The MCID for the Pain domain was 0.20 and 0.98 for Appearance. 
      Because these patients were generally in good health, a minimal though 
      significant change in activity was observed, such that the calculated MCID was 
      within the measurement error. As expected, the largest and most important change 
      was in the Appearance domain. Future studies are needed to determine the MCID for 
      the mental domain and the total SRS score and to further validate the MCID values 
      in this study.
FAU - Carreon, Leah Y
AU  - Carreon LY
AD  - Norton Leatherman Spine Center, Louisville, KY 40202, USA. 
      leah.carreon@nortonhealthcare.org
FAU - Sanders, James O
AU  - Sanders JO
FAU - Diab, Mohammad
AU  - Diab M
FAU - Sucato, Daniel J
AU  - Sucato DJ
FAU - Sturm, Peter F
AU  - Sturm PF
FAU - Glassman, Steven D
AU  - Glassman SD
CN  - Spinal Deformity Study Group
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Spine (Phila Pa 1976)
JT  - Spine
JID - 7610646
SB  - IM
MH  - Adolescent
MH  - Area Under Curve
MH  - Child
MH  - Female
MH  - Humans
MH  - Male
MH  - Pain/*surgery
MH  - *Patient Satisfaction
MH  - Quality of Life
MH  - ROC Curve
MH  - Scoliosis/*surgery
MH  - *Spinal Fusion
MH  - Surveys and Questionnaires
MH  - Treatment Outcome
EDAT- 2010/04/17 06:00
MHDA- 2011/02/05 06:00
CRDT- 2010/04/17 06:00
PHST- 2010/04/17 06:00 [entrez]
PHST- 2010/04/17 06:00 [pubmed]
PHST- 2011/02/05 06:00 [medline]
AID - 10.1097/BRS.0b013e3181c61fd7 [doi]
PST - ppublish
SO  - Spine (Phila Pa 1976). 2010 Nov 1;35(23):2079-83. doi: 
      10.1097/BRS.0b013e3181c61fd7.