PMID- 20398353
OWN - NLM
STAT- MEDLINE
DCOM- 20100629
LR  - 20211020
IS  - 1471-2202 (Electronic)
IS  - 1471-2202 (Linking)
VI  - 11
DP  - 2010 Apr 16
TI  - Maturation of auditory temporal integration and inhibition assessed with 
      event-related potentials (ERPs).
PG  - 49
LID - 10.1186/1471-2202-11-49 [doi]
AB  - BACKGROUND: We examined development of auditory temporal integration and 
      inhibition by assessing electrophysiological responses to tone pairs separated by 
      interstimulus intervals (ISIs) of 25, 50, 100, 200, 400, and 800 ms in 28 
      children aged 7 to 9 years, and 15 adults. RESULTS: In adults a distinct neural 
      response was elicited to tones presented at ISIs of 25 ms or longer, whereas in 
      children this was only seen in response to tones presented at ISIs above 100 ms. 
      In adults, late N1 amplitude was larger for the second tone of the tone pair when 
      separated by ISIs as short as 100 ms, consistent with the perceptual integration 
      of successive stimuli within the temporal window of integration. In contrast, 
      children showed enhanced negativity only when tone pairs were separated by ISIs 
      of 200 ms. In children, the amplitude of the P1 component was attenuated at ISIs 
      below 200 ms, consistent with a refractory process. CONCLUSIONS: These results 
      indicate that adults integrate sequential auditory information into smaller 
      temporal segments than children. These results suggest that there are marked 
      maturational changes from childhood to adulthood in the perceptual processes 
      underpinning the grouping of incoming auditory sensory information, and that 
      electrophysiological measures provide a sensitive, non-invasive method allowing 
      further examination of these changes.
FAU - Fox, Allison M
AU  - Fox AM
AD  - School of Psychology, University of Western Australia, Perth, Australia. 
      allison.fox@uwa.edu.au.
FAU - Anderson, Mike
AU  - Anderson M
FAU - Reid, Corinne
AU  - Reid C
FAU - Smith, Tim
AU  - Smith T
FAU - Bishop, Dorothy V M
AU  - Bishop DV
LA  - eng
GR  - 082498/WT_/Wellcome Trust/United Kingdom
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20100416
PL  - England
TA  - BMC Neurosci
JT  - BMC neuroscience
JID - 100966986
SB  - IM
MH  - Acoustic Stimulation
MH  - Adult
MH  - Aging/*physiology
MH  - Auditory Cortex/*growth & development
MH  - Auditory Pathways/growth & development
MH  - Auditory Perception/*physiology
MH  - Auditory Threshold/physiology
MH  - Child
MH  - Electroencephalography
MH  - Evoked Potentials/*physiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Neural Inhibition/physiology
MH  - Neuropsychological Tests
MH  - Perceptual Masking/physiology
MH  - Reaction Time/physiology
MH  - Signal Processing, Computer-Assisted
MH  - Sound Localization/*physiology
MH  - Time Factors
MH  - Time Perception/*physiology
MH  - Young Adult
PMC - PMC2868034
EDAT- 2010/04/20 06:00
MHDA- 2010/06/30 06:00
PMCR- 2010/04/16
CRDT- 2010/04/20 06:00
PHST- 2009/08/06 00:00 [received]
PHST- 2010/04/16 00:00 [accepted]
PHST- 2010/04/20 06:00 [entrez]
PHST- 2010/04/20 06:00 [pubmed]
PHST- 2010/06/30 06:00 [medline]
PHST- 2010/04/16 00:00 [pmc-release]
AID - 1471-2202-11-49 [pii]
AID - 10.1186/1471-2202-11-49 [doi]
PST - epublish
SO  - BMC Neurosci. 2010 Apr 16;11:49. doi: 10.1186/1471-2202-11-49.