PMID- 20404429
OWN - NLM
STAT- MEDLINE
DCOM- 20101130
LR  - 20100420
IS  - 1735-8582 (Print)
IS  - 1735-8582 (Linking)
VI  - 4
IP  - 2
DP  - 2010 Apr
TI  - Seroprevalence of herpes simplex virus-2 in kidney transplant recipients: a 
      single-center experience.
PG  - 158-61
AB  - INTRODUCTION: Viral infections are a real threat in kidney transplant recipients 
      because of their immunocompromised condition. This study aimed to evaluate herpes 
      simplex virus-2 (HSV-2) seropositivity among kidney transplant recipients. 
      MATERIALS AND METHODS: Serum samples of 91 kidney transplant recipients from 
      Urmia, Iran, were examined serologically for antibodies against HSV-2 using an 
      enzyme-linked immunosorbent assay. RESULTS: The mean time from transplantation at 
      HSV-2 testing was 5.04 +/- 4.45 years. The anti-HSV-2 immunoglobulin G antibody 
      was positive in 5.4% of the kidney transplant recipients. Seropositive patients 
      did not present any clinical manifestations of genital herpes infection. There 
      was no association between HSV-2 seropositivity and age, gender, history of 
      hemodialysis and transplantation, blood transfusion, or immunosuppressive 
      regimen. CONCLUSIONS: Seroprevalence of HSV-2 is not high among our kidney 
      transplant recipients. However, it remains a source of concern, considering the 
      compromised immune system in this specific population.
FAU - Rostamzadeh Khameneh, Zakieh
AU  - Rostamzadeh Khameneh Z
AD  - Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran. 
      nariman256@gmail.com
FAU - Sepehrvand, Nariman
AU  - Sepehrvand N
FAU - Taghizadeh-Afshari, Ali
AU  - Taghizadeh-Afshari A
FAU - Motazakker, Morteza
AU  - Motazakker M
FAU - Ghafari, Ali
AU  - Ghafari A
FAU - Masudi, Sima
AU  - Masudi S
LA  - eng
PT  - Journal Article
PL  - Iran
TA  - Iran J Kidney Dis
JT  - Iranian journal of kidney diseases
JID - 101316967
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Child
MH  - Female
MH  - Herpes Simplex/*epidemiology
MH  - Herpesvirus 2, Human/*immunology
MH  - Humans
MH  - Iran/epidemiology
MH  - *Kidney Transplantation
MH  - Male
MH  - Middle Aged
MH  - Seroepidemiologic Studies
MH  - Young Adult
EDAT- 2010/04/21 06:00
MHDA- 2010/12/14 06:00
CRDT- 2010/04/21 06:00
PHST- 2010/04/21 06:00 [entrez]
PHST- 2010/04/21 06:00 [pubmed]
PHST- 2010/12/14 06:00 [medline]
AID - 215/189 [pii]
PST - ppublish
SO  - Iran J Kidney Dis. 2010 Apr;4(2):158-61.