PMID- 20426060 OWN - NLM STAT- MEDLINE DCOM- 20100607 LR - 20190907 VI - 12 IP - Pt 1 DP - 2009 TI - MR to ultrasound image registration for guiding prostate biopsy and interventions. PG - 787-94 AB - A method is described for registering preoperative magnetic resonance (MR) to intraoperative transrectal ultrasound (TRUS) images of the prostate gland. A statistical motion model (SMM) of the prostate is first built using training data provided by biomechanical simulations of the motion of a patient-specific finite element model, derived from a preoperative MR image. The SMM is then registered to a 3D TRUS image by maximising the likelihood of the shape of an SMM instance given a voxel-intensity-based feature, which represents an estimate of normal vector at the surface of the prostate gland. Using data acquired from 7 patients, the accuracy of registering T2 MR to 3D TRUS images was evaluated using anatomical landmarks inside the gland. The results show that the proposed registration method has a root-mean-square target registration error of 2.66 mm. FAU - Hu, Yipeng AU - Hu Y AD - Centre for Medical Image Computing, University College London, London, UK. FAU - Ahmed, Hashim Uddin AU - Ahmed HU FAU - Allen, Clare AU - Allen C FAU - Pendse, Doug AU - Pendse D FAU - Sahu, Mahua AU - Sahu M FAU - Emberton, Mark AU - Emberton M FAU - Hawkes, David AU - Hawkes D FAU - Barratt, Dean AU - Barratt D LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Germany TA - Med Image Comput Comput Assist Interv JT - Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention JID - 101249582 SB - IM MH - Algorithms MH - Artificial Intelligence MH - Biopsy/*methods MH - Humans MH - Image Enhancement/methods MH - Image Interpretation, Computer-Assisted/*methods MH - Imaging, Three-Dimensional/*methods MH - Male MH - Pattern Recognition, Automated/*methods MH - Prostatic Neoplasms/*diagnosis MH - Radiography, Interventional/methods MH - Reproducibility of Results MH - Sensitivity and Specificity MH - *Subtraction Technique MH - Surgery, Computer-Assisted/*methods EDAT- 2009/01/01 00:00 MHDA- 2010/06/09 06:00 CRDT- 2010/04/30 06:00 PHST- 2010/04/30 06:00 [entrez] PHST- 2009/01/01 00:00 [pubmed] PHST- 2010/06/09 06:00 [medline] AID - 10.1007/978-3-642-04268-3_97 [doi] PST - ppublish SO - Med Image Comput Comput Assist Interv. 2009;12(Pt 1):787-94. doi: 10.1007/978-3-642-04268-3_97.