PMID- 20432099
OWN - NLM
STAT- MEDLINE
DCOM- 20101014
LR  - 20191210
IS  - 1944-0057 (Electronic)
IS  - 1944-0057 (Linking)
VI  - 27
IP  - 7
DP  - 2010 Jul
TI  - Simultaneous determination of residues of trichlorfon and dichlorvos in animal 
      tissues by LC-MS/MS.
PG  - 983-8
LID - 10.1080/19440041003671270 [doi]
AB  - Trichlorfon is a thermally unstable insecticide that can be easily decomposed to 
      dichlorvos at high temperatures. In this study, a liquid chromatography-tandem 
      mass spectrometry (LC-MS/MS) method was developed for simultaneous determination 
      of the residues of trichlorfon and dichlorvos in animal tissues. Trichlorfon and 
      dichlorvos in animal tissues were extracted with dichloromethane, 
      homogenized/shaken, concentrated, and determined by LC-MS/MS. The two 
      insecticides can be effectively separated and individually determined. The limits 
      of detection (LODs) of trichlorfon and dichlorvos were 0.04 and 0.07 microg 
      kg(-1), respectively; the limits of quantification (LOQs) of the two insecticides 
      were both 5 microg kg(-1). The average recoveries for three spiked blank samples 
      at 10, 20 and 40 microg kg(-1) were in the range 85-106%, with relative standard 
      deviations (RSDs) below 10.6%, which falls in a reasonable range for the analysis 
      of the two insecticides in animal-derived foods. The method is fit-for-purpose 
      for the simultaneous determination of residues of trichlorfon and dichlorvos in 
      animal tissues.
FAU - Wang, G M
AU  - Wang GM
AD  - Key Laboratory of Biorheology Science and Technology Under Ministry of Education, 
      College of Bioengineering, Chongqing University, Chongqing 400044, China.
FAU - Dai, H
AU  - Dai H
FAU - Li, Y G
AU  - Li YG
FAU - Li, X L
AU  - Li XL
FAU - Zhang, J Z
AU  - Zhang JZ
FAU - Zhang, L
AU  - Zhang L
FAU - Fu, Y Y
AU  - Fu YY
FAU - Li, Z G
AU  - Li ZG
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Validation Study
PL  - England
TA  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess
JT  - Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & 
      risk assessment
JID - 101485040
RN  - 0 (Insecticides)
RN  - 0 (Pesticide Residues)
RN  - 7U370BPS14 (Dichlorvos)
RN  - DBF2DG4G2K (Trichlorfon)
SB  - IM
MH  - Analytic Sample Preparation Methods
MH  - Animals
MH  - Chromatography, High Pressure Liquid
MH  - Dichlorvos/*analysis/chemistry
MH  - *Food Contamination/prevention & control
MH  - Food Inspection/*methods
MH  - Insecticides/*analysis/chemistry
MH  - Limit of Detection
MH  - Liver/chemistry
MH  - Meat/*analysis
MH  - Meat Products/analysis
MH  - Muscle, Skeletal/chemistry
MH  - Pesticide Residues/*analysis/chemistry/isolation & purification
MH  - Reproducibility of Results
MH  - Spectrometry, Mass, Electrospray Ionization
MH  - Sus scrofa
MH  - Tandem Mass Spectrometry
MH  - Trichlorfon/*analysis/chemistry
EDAT- 2010/05/01 06:00
MHDA- 2010/10/15 06:00
CRDT- 2010/05/01 06:00
PHST- 2010/05/01 06:00 [entrez]
PHST- 2010/05/01 06:00 [pubmed]
PHST- 2010/10/15 06:00 [medline]
AID - 921716212 [pii]
AID - 10.1080/19440041003671270 [doi]
PST - ppublish
SO  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2010 
      Jul;27(7):983-8. doi: 10.1080/19440041003671270.