PMID- 20434868
OWN - NLM
STAT- MEDLINE
DCOM- 20101116
LR  - 20131121
IS  - 1873-6483 (Electronic)
IS  - 0740-5472 (Linking)
VI  - 39
IP  - 1
DP  - 2010 Jul
TI  - Self-treatment: illicit buprenorphine use by opioid-dependent treatment seekers.
PG  - 41-50
LID - 10.1016/j.jsat.2010.03.014 [doi]
AB  - Outpatient-based opioid treatment (OBOT) with buprenorphine is an important 
      treatment for people with opioid dependence. No quantitative empirical research 
      has examined rationales for use of illicit buprenorphine by U.S. opioid-dependent 
      treatment seekers. The current study sequentially screened OBOT admissions (n = 
      129) during a 6-month period in 2009. This study had two stages: (a) a 
      cross-sectional epidemiological analysis of new intakes and existing patients 
      already receiving a legal OBOT prescription (n = 78) and (b) a prospective 
      longitudinal cohort design that followed 76% of the initial participants for 3 
      months of treatment (n = 42). The primary aims were to establish 2009 prevalence 
      rates for illicit buprenorphine use among people seeking OBOT treatment, to use 
      quantitative methods to investigate reasons for this illicit use, and to examine 
      the effect of OBOT treatment on illicit buprenorphine use behavior. These data 
      demonstrate a decrease in illicit use when opioid-dependent treatment seekers 
      gain access to legal prescriptions. These data also suggest that the use of 
      illicit buprenorphine rarely represents an attempt to attain euphoria. Rather, 
      illicit use is associated with attempted self-treatment of symptoms of opioid 
      dependence, pain, and depression.
CI  - Copyright 2010 Elsevier Inc. All rights reserved.
FAU - Schuman-Olivier, Zev
AU  - Schuman-Olivier Z
AD  - Cambridge Health Alliance, Department of Psychiatry, Harvard Medical School, 
      United States. zschuman@partners.org
FAU - Albanese, Mark
AU  - Albanese M
FAU - Nelson, Sarah E
AU  - Nelson SE
FAU - Roland, Lolita
AU  - Roland L
FAU - Puopolo, Francyne
AU  - Puopolo F
FAU - Klinker, Lauren
AU  - Klinker L
FAU - Shaffer, Howard J
AU  - Shaffer HJ
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Subst Abuse Treat
JT  - Journal of substance abuse treatment
JID - 8500909
RN  - 0 (Narcotics)
RN  - 40D3SCR4GZ (Buprenorphine)
SB  - IM
MH  - Adult
MH  - Buprenorphine/administration & dosage/*adverse effects
MH  - Cohort Studies
MH  - Cross-Sectional Studies
MH  - Depression/etiology/psychology
MH  - Female
MH  - Humans
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - Narcotics/administration & dosage/*adverse effects
MH  - Opioid-Related Disorders/epidemiology/psychology/*rehabilitation
MH  - Pain/etiology/psychology
MH  - Prevalence
MH  - Prospective Studies
MH  - Self Medication/*psychology
MH  - United States/epidemiology
EDAT- 2010/05/04 06:00
MHDA- 2010/11/17 06:00
CRDT- 2010/05/04 06:00
PHST- 2009/11/18 00:00 [received]
PHST- 2010/03/08 00:00 [revised]
PHST- 2010/03/22 00:00 [accepted]
PHST- 2010/05/04 06:00 [entrez]
PHST- 2010/05/04 06:00 [pubmed]
PHST- 2010/11/17 06:00 [medline]
AID - S0740-5472(10)00075-9 [pii]
AID - 10.1016/j.jsat.2010.03.014 [doi]
PST - ppublish
SO  - J Subst Abuse Treat. 2010 Jul;39(1):41-50. doi: 10.1016/j.jsat.2010.03.014.