PMID- 20437318
OWN - NLM
STAT- MEDLINE
DCOM- 20100816
LR  - 20231103
IS  - 1938-1352 (Electronic)
IS  - 0748-7711 (Print)
IS  - 0748-7711 (Linking)
VI  - 46
IP  - 9
DP  - 2009
TI  - Reference equation for 6-minute walk in individuals with Parkinson disease.
PG  - 1121-6
AB  - Normal values, as well as determining factors, for the 6-minute walk test are 
      available for nondisabled adults, but less is known about individuals with 
      Parkinson disease (PD). This study created a PD-specific reference equation and 
      identified unique factors associated with 6-minute walk distance (6MWD). Eighty 
      individuals (mean +/- standard deviation [SD] age: 66.3 +/- 9.8 yr) with mild to 
      moderate PD underwent a neurological examination and completed a small battery of 
      tests to assess their balance confidence, fall risk, mobility, and balance. Their 
      mean +/- SD 6MWD was 394.1 +/- 98.4 m (95% confidence interval: 370.0-418.1). 
      Stepwise multiple regression analysis demonstrated that timed up-and-go (TUG) 
      test, one-leg stance (OLS) test, and sex were significant independent 
      contributors to 6MWD and accounted for 56.6% of the variance. The resulting 
      PD-specific regression equation is 6MWD pred = 543.06 + (-10.83 degrees TUG) + 
      (2.04 degrees OLS) + (-44.44 degrees sex). (For sex, 0 = female, 1 = male.) 
      Future interpretation of 6MWD in individuals with PD may be enhanced if expressed 
      as a percentage of the value predicted utilizing this reference equation.
FAU - Falvo, Michael J
AU  - Falvo MJ
AD  - Program in Physical Therapy and Department of Anatomy and Neurobiology and 
      Department of Neurology, Washington University School of Medicine, St. Louis, MO 
      63110, USA.
FAU - Earhart, Gammon M
AU  - Earhart GM
LA  - eng
GR  - K01 HD048437/HD/NICHD NIH HHS/United States
GR  - 1K01HD048437/HD/NICHD NIH HHS/United States
GR  - K01 HD048437-05/HD/NICHD NIH HHS/United States
GR  - T32 HD007434-17/HD/NICHD NIH HHS/United States
GR  - T32 HD007434/HD/NICHD NIH HHS/United States
GR  - T32HD007434/HD/NICHD NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PL  - United States
TA  - J Rehabil Res Dev
JT  - Journal of rehabilitation research and development
JID - 8410047
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - *Disability Evaluation
MH  - *Exercise Test
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Parkinson Disease/*physiopathology
MH  - Reference Values
MH  - *Walking
PMC - PMC2867249
MID - NIHMS158959
EDAT- 2009/01/01 00:00
MHDA- 2010/08/17 06:00
PMCR- 2010/05/11
CRDT- 2010/05/04 06:00
PHST- 2010/05/04 06:00 [entrez]
PHST- 2009/01/01 00:00 [pubmed]
PHST- 2010/08/17 06:00 [medline]
PHST- 2010/05/11 00:00 [pmc-release]
AID - 10.1682/jrrd.2009.04.0046 [doi]
PST - ppublish
SO  - J Rehabil Res Dev. 2009;46(9):1121-6. doi: 10.1682/jrrd.2009.04.0046.