PMID- 20438788 OWN - NLM STAT- MEDLINE DCOM- 20110131 LR - 20221207 IS - 1879-1166 (Electronic) IS - 0198-8859 (Linking) VI - 71 IP - 9 DP - 2010 Sep TI - Identification of a novel HLA-A allele, HLA-A*0355, in a Brazilian family of eastern European descendents. PG - 920-1 LID - 10.1016/j.humimm.2010.04.006 [doi] AB - The new human leukocyte antigen (HLA) class I allele, HLA-A*0355 was identified in a Brazilian family. Our sequence analysis detected a mismatch located in exon 2, codon 86, at position 258 (C-->A) that results in a nonsilent and nonconservative substitution with the replacement of asparagine by lysine. Substitutions located at this oligosaccharide attachment site of the protein were observed in only other four classic HLA class I sequences, indicating a highly conserved peptide site however its function remains unknown. CI - Copyright 2010. Published by Elsevier Inc. FAU - Mattar, Sibelle Botogosque AU - Mattar SB AD - Laboratory of Immunogenetics and Histocompatibility, Genetics Department, Universidade Federal do Parana, Curitiba, Brazil. FAU - Uehara, Clineu Julien Seki AU - Uehara CJ FAU - Ribas, Fernanda AU - Ribas F FAU - Poerner, Fabiana AU - Poerner F FAU - de Rezende, Gorete Ynaquievi Tomaz AU - de Rezende GY FAU - Vargas, Rafael Gustavo AU - Vargas RG FAU - Wowk, Pryscilla Fanini AU - Wowk PF FAU - da Graca Bicalho, Maria AU - da Graca Bicalho M LA - eng SI - GENBANK/GQ250940 PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20100514 PL - United States TA - Hum Immunol JT - Human immunology JID - 8010936 RN - 0 (HLA-A Antigens) RN - 0 (HLA-A*02:01 antigen) RN - 0 (HLA-A*03:01 antigen) RN - 0 (HLA-A2 Antigen) RN - 0 (HLA-A3 Antigen) SB - IM MH - Adult MH - *Alleles MH - Amino Acid Substitution/genetics MH - Base Sequence/genetics MH - Brazil MH - Cloning, Molecular MH - Europe, Eastern/ethnology MH - Female MH - Genotype MH - HLA-A Antigens/*genetics MH - HLA-A2 Antigen MH - HLA-A3 Antigen MH - Haplotypes MH - Histocompatibility Testing MH - Humans MH - Molecular Sequence Data MH - Sequence Analysis, DNA MH - Siblings MH - White People/*genetics EDAT- 2010/05/05 06:00 MHDA- 2011/02/01 06:00 CRDT- 2010/05/05 06:00 PHST- 2010/01/29 00:00 [received] PHST- 2010/03/31 00:00 [revised] PHST- 2010/04/23 00:00 [accepted] PHST- 2010/05/05 06:00 [entrez] PHST- 2010/05/05 06:00 [pubmed] PHST- 2011/02/01 06:00 [medline] AID - S0198-8859(10)00109-6 [pii] AID - 10.1016/j.humimm.2010.04.006 [doi] PST - ppublish SO - Hum Immunol. 2010 Sep;71(9):920-1. doi: 10.1016/j.humimm.2010.04.006. Epub 2010 May 14.