PMID- 20444003
OWN - NLM
STAT- MEDLINE
DCOM- 20110302
LR  - 20101105
IS  - 1600-0684 (Electronic)
IS  - 0047-2565 (Linking)
VI  - 39
IP  - 6
DP  - 2010 Dec
TI  - Retrospective case-control study of hyperglycemia in group-housed, mature female 
      cynomolgus macaques (Macaca fascicularis).
PG  - 408-16
LID - 10.1111/j.1600-0684.2010.00417.x [doi]
AB  - BACKGROUND: Captive cynomolgus macaques are prone to obesity, increasing their 
      risk for developing hyperglycemia and type 2 diabetes mellitus (T2DM). Social 
      rank may be a contributing risk factor predisposing macaques to adverse health 
      events. METHODS: Using retrospective health records from 259 animals, a matched 
      case-control study was conducted to assess risk factors for developing 
      hyperglycemia in group-housed, adult females aged 10 or older. Univariable exact 
      and conditional logistic regression models were used to analyze the data. RESULT: 
      The odds of developing hyperglycemia were significantly greater in animals with 
      more frequent counts of injury. Similarly, subordinate animals had higher odds of 
      developing hyperglycemia than affiliates. CONCLUSIONS: Subordinate social status 
      may increase the risk of hyperglycemia in mature female cynomolgus macaques. 
      Opportunities for subordinates to alter feeding strategies are reduced in 
      captivity. This may be associated with increased social stress around feeding, 
      and for animals housed long-term could predispose them to obesity and 
      hyperglycemia.
CI  - (c) 2010 John Wiley & Sons A/S.
FAU - Bauer, S A
AU  - Bauer SA
AD  - Department of Population Medicine, University of Guelph, Guelph, ON, Canada.
FAU - Leslie, K E
AU  - Leslie KE
FAU - Pearl, D L
AU  - Pearl DL
FAU - Fournier, J
AU  - Fournier J
FAU - Turner, P V
AU  - Turner PV
LA  - eng
PT  - Journal Article
PL  - Denmark
TA  - J Med Primatol
JT  - Journal of medical primatology
JID - 0320626
SB  - IM
MH  - Animals
MH  - Behavior, Animal
MH  - Case-Control Studies
MH  - Female
MH  - *Housing, Animal
MH  - Hyperglycemia/*veterinary
MH  - *Macaca fascicularis
MH  - Monkey Diseases/*blood
MH  - Retrospective Studies
MH  - Social Dominance
EDAT- 2010/05/07 06:00
MHDA- 2011/03/03 06:00
CRDT- 2010/05/07 06:00
PHST- 2010/05/07 06:00 [entrez]
PHST- 2010/05/07 06:00 [pubmed]
PHST- 2011/03/03 06:00 [medline]
AID - JMP417 [pii]
AID - 10.1111/j.1600-0684.2010.00417.x [doi]
PST - ppublish
SO  - J Med Primatol. 2010 Dec;39(6):408-16. doi: 10.1111/j.1600-0684.2010.00417.x.