PMID- 20444484
OWN - NLM
STAT- MEDLINE
DCOM- 20100812
LR  - 20161125
IS  - 1879-1298 (Electronic)
IS  - 0045-6535 (Linking)
VI  - 80
IP  - 2
DP  - 2010 Jun
TI  - Modeling of a short-path distillation process to remove persistent organic 
      pollutants in fish oil based on process parameters and quantitative structure 
      properties relationships.
PG  - 83-92
LID - 10.1016/j.chemosphere.2010.04.016 [doi]
AB  - A factorial experimental design based on temperature, feed rate and addition of 
      "working fluid" (WF; fatty acid ethyl esters) was used to model a short-path 
      distillation process applied for removal of persistent organic pollutants (POPs) 
      in fish oil. Decontamination effect was assessed by measuring the level of 
      polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), dioxin-like 
      polychlorinated biphenyls (DL-PCBs) and polybrominated diphenylethers (PBDEs). 
      The average reduction in chemical concentration of the individual PCDD, PCDF, 
      DL-PCB and PBDE congeners was linearly dependent on the number of chlorine or 
      bromine substitutions within each homologue group. DL-PCB and PBDE congeners 
      could also be separated based on ortho-substitution. The quantitative structure 
      properties relationships (QSPR) were combined with process parameters to 
      establish response surface models for each homologue congener group based on 
      partial least squares regression (PLSR). Cross validated predictive ability of 
      the models was in the 4-9% range. Generally high temperature, low feed rate and 
      WF addition improved the decontamination efficiency. The WHO-PCDD/F-PCB-TEQ level 
      could be reduced by up to 98% based on the best experimental settings with 
      residual concentration considerably below present maximum permitted levels in 
      European food and feed legislations.
CI  - Copyright (c) 2010 Elsevier Ltd. All rights reserved.
FAU - Oterhals, Age
AU  - Oterhals A
AD  - Nofima Ingrediens, Kjerreidviken 16, Fyllingsdalen, Norway. 
      aage.oterhals@nofima.no
FAU - Kvamme, Bjorn
AU  - Kvamme B
FAU - Berntssen, Marc H G
AU  - Berntssen MH
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20100504
PL  - England
TA  - Chemosphere
JT  - Chemosphere
JID - 0320657
RN  - 0 (Benzofurans)
RN  - 0 (Dibenzofurans, Polychlorinated)
RN  - 0 (Fish Oils)
RN  - 0 (Halogenated Diphenyl Ethers)
RN  - 0 (Polychlorinated Dibenzodioxins)
RN  - 0 (Water Pollutants, Chemical)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Benzofurans/analysis
MH  - Dibenzofurans, Polychlorinated
MH  - Distillation/*methods
MH  - Fish Oils/*chemistry/isolation & purification
MH  - Halogenated Diphenyl Ethers/analysis
MH  - *Models, Chemical
MH  - Polychlorinated Biphenyls/analysis
MH  - Polychlorinated Dibenzodioxins/analogs & derivatives/analysis
MH  - Water Pollutants, Chemical/*analysis/chemistry
EDAT- 2010/05/07 06:00
MHDA- 2010/08/13 06:00
CRDT- 2010/05/07 06:00
PHST- 2010/01/05 00:00 [received]
PHST- 2010/03/24 00:00 [revised]
PHST- 2010/04/02 00:00 [accepted]
PHST- 2010/05/07 06:00 [entrez]
PHST- 2010/05/07 06:00 [pubmed]
PHST- 2010/08/13 06:00 [medline]
AID - S0045-6535(10)00423-6 [pii]
AID - 10.1016/j.chemosphere.2010.04.016 [doi]
PST - ppublish
SO  - Chemosphere. 2010 Jun;80(2):83-92. doi: 10.1016/j.chemosphere.2010.04.016. Epub 
      2010 May 4.