PMID- 20445448
OWN - NLM
STAT- MEDLINE
DCOM- 20100830
LR  - 20100521
IS  - 1531-7013 (Electronic)
IS  - 1087-2418 (Linking)
VI  - 15
IP  - 3
DP  - 2010 Jun
TI  - Current status of living donor small bowel transplantation.
PG  - 346-8
LID - 10.1097/MOT.0b013e3283398fa4 [doi]
AB  - PURPOSE OF REVIEW: To analyze the current status of living donor intestinal 
      transplantation (LDIT) as a treatment option for intestinal failure. RECENT 
      FINDINGS: Long-term outcomes from LDIT and combined living donor intestinal/liver 
      transplantation (CLDILT) are comparable with those from transplantation using 
      deceased donors. In certain life-threatening situations, especially in pediatric 
      patients, this strategy may offer potential advantages. SUMMARY: According United 
      Network for Organ Sharing (UNOS) data children with intestinal failure affected 
      by liver disease secondary to parenteral nutrition have the highest mortality on 
      a waiting list compared with all candidates for solid organ transplantation. 
      Elective nature of CLDILT offers multiple advantages for this patient population. 
      LDIT also could be life-saving option for patients with intestinal failure who 
      run out of venous access. Optimal timing, short ischemia time and good human 
      leukocyte antigen (HLA) matching may contribute to lower postoperative 
      complications. Current literature suggests that living intestinal donors 
      experience very low morbidity and high level of satisfaction.
FAU - Tzvetanov, Ivo G
AU  - Tzvetanov IG
AD  - Division of Transplantation, Department of Surgery, University of Illinois at 
      Chicago, Illinois, USA.
FAU - Oberholzer, Jose
AU  - Oberholzer J
FAU - Benedetti, Enrico
AU  - Benedetti E
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Opin Organ Transplant
JT  - Current opinion in organ transplantation
JID - 9717388
SB  - IM
MH  - Child
MH  - Child, Preschool
MH  - Humans
MH  - Infant
MH  - Intestine, Small/*transplantation
MH  - Liver Failure/etiology/mortality/*surgery
MH  - *Liver Transplantation/adverse effects/mortality
MH  - Living Donors/*supply & distribution
MH  - Parenteral Nutrition, Total/adverse effects
MH  - Patient Selection
MH  - Risk Assessment
MH  - Risk Factors
MH  - Short Bowel Syndrome/mortality/*surgery
MH  - Time Factors
MH  - Treatment Outcome
MH  - Waiting Lists
RF  - 24
EDAT- 2010/05/07 06:00
MHDA- 2010/08/31 06:00
CRDT- 2010/05/07 06:00
PHST- 2010/05/07 06:00 [entrez]
PHST- 2010/05/07 06:00 [pubmed]
PHST- 2010/08/31 06:00 [medline]
AID - 10.1097/MOT.0b013e3283398fa4 [doi]
PST - ppublish
SO  - Curr Opin Organ Transplant. 2010 Jun;15(3):346-8. doi: 
      10.1097/MOT.0b013e3283398fa4.