PMID- 2044549
OWN - NLM
STAT- MEDLINE
DCOM- 19910716
LR  - 20190510
IS  - 0195-668X (Print)
IS  - 0195-668X (Linking)
VI  - 12
IP  - 2
DP  - 1991 Feb
TI  - Risk factors for operative mortality and morbidity in patients undergoing 
      coronary artery bypass surgery for stable angina pectoris.
PG  - 162-8
AB  - Risk factors for a poor early outcome of surgery for stable angina pectoris were 
      evaluated in 2659 consecutive patients from a defined population. The total 
      operative mortality (death within 30 days after surgery) was 2.6% and the 
      frequency of myocardial injury (increase in S-ASAT to greater than 2.0 mu kat l-1 
      and in S-CKMB to greater than 1.5 mu kat l-1 within 48 h postoperatively or death 
      in the operating room) 14%. Mortality was related to New York Heart Association 
      (NYHA) classification (P less than 0.001), age (less than or greater than 70 
      years, P = 0.001), duration of symptoms (less than or greater than 8 years, P = 
      0.001), aortic cross-clamp (ACC) time (P less than 0.001), and cardiopulmonary 
      bypass (CBP) time (P less than 0.001). A multivariate analysis showed that the 
      combination of NYHA class, ACC time and age best predicted operative mortality. 
      Myocardial injury was related to NYHA functional class (P less than 0.001), 
      duration of symptoms (P less than 0.001), regrafting procedure (P less than 
      0.001), cardiac related dyspnoea (P = 0.015), ACC time (P = 0.001), CPB time (P = 
      0.001), relative volume of cardioplegic solution (P less than 0.001), and 
      thromboendarterectomy procedure (P = 0.004). The set of variables that best 
      predicted myocardial injury consisted of ACC time, relative volume cardioplegic 
      solution, NYHA class, regrafting procedure and duration of symptoms. However, 
      these risk factors indicated only moderately high risks, and high-risk patients 
      could not be selected with sufficient accuracy.
FAU - Stahle, E
AU  - Stahle E
AD  - Department of Thoracic and Cardiovascular Surgery, University Hospital, Uppsala, 
      Sweden.
FAU - Bergstrom, R
AU  - Bergstrom R
FAU - Holmberg, L
AU  - Holmberg L
FAU - Nystrom, S O
AU  - Nystrom SO
FAU - Hansson, H E
AU  - Hansson HE
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Eur Heart J
JT  - European heart journal
JID - 8006263
SB  - IM
MH  - Adult
MH  - Aged
MH  - Angina Pectoris/*surgery
MH  - *Cause of Death
MH  - *Coronary Artery Bypass
MH  - Coronary Disease/*surgery
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Arrest/mortality
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/mortality
MH  - Myocardial Reperfusion Injury/mortality
MH  - Postoperative Complications/*mortality
MH  - Risk Factors
EDAT- 1991/02/01 00:00
MHDA- 1991/02/01 00:01
CRDT- 1991/02/01 00:00
PHST- 1991/02/01 00:00 [pubmed]
PHST- 1991/02/01 00:01 [medline]
PHST- 1991/02/01 00:00 [entrez]
AID - 10.1093/oxfordjournals.eurheartj.a059863 [doi]
PST - ppublish
SO  - Eur Heart J. 1991 Feb;12(2):162-8. doi: 10.1093/oxfordjournals.eurheartj.a059863.