PMID- 20447205
OWN - NLM
STAT- MEDLINE
DCOM- 20100914
LR  - 20100507
IS  - 1443-1661 (Electronic)
IS  - 0915-5635 (Linking)
VI  - 22
IP  - 2
DP  - 2010 Apr
TI  - Endoscopic diagnosis of intraductal papillary-mucinous neoplasm of the pancreas 
      by means of peroral pancreatoscopy using a small-diameter videoscope and 
      narrow-band imaging.
PG  - 119-23
LID - 10.1111/j.1443-1661.2010.00926.x [doi]
AB  - BACKGROUND: Intraductal papillary-mucinous neoplasm (IPMN) is an intraductal 
      tumor in which the mucin-producing epithelium shows proliferated papillary and a 
      wide variety of pathological changes ranging from hyperplasia to adenocarcinoma. 
      Therefore, it is important to determine whether an IPMN is benign or malignant. 
      In the present study of patients with IPMN, the protrusion was observed by a 
      peroral pancreatoscopy (PPS) using a small-diameter videoscope and narrow-band 
      imaging (NBI). We carried out the differential diagnosis of benign lesion to 
      malignant lesion. METHODS: Between April 2003 and May 2009, PPS using a 
      small-diameter videoscope by means of NBI was carried out on 21 hospitalized 
      patients with IPMN (10 cases of adenocarcinoma, 11 cases of adenoma or 
      hyperplasia; 14 males and seven females, with a mean age of 69.4 years). RESULTS: 
      Fifteen focal lesions of the 16 cases in the head of the pancreas (93.7%) and 
      four focal lesions of the five cases in the pancreatic body (80%) were 
      observable, whereas two lesions (adenocarcinoma in the pancreatic body, and 
      adenoma in the uncus of pancreas) were not observable. Endoscopically, seven 
      cases were classified as villous type and two cases as vegetative type, and nine 
      cases were diagnosed as adenocarcinoma. Ten cases with sessile type or 
      semipedunculated type were diagnosed as adenoma or hyperplasia. Vascular patterns 
      and protrusions were detected more clearly in the NBI images than under white 
      light observation. CONCLUSIONS: When combined with a videoscope and NBI, 
      pancreatoscopy provided a clear image and was useful for evaluating whether the 
      IPMN was benign or malignant.
FAU - Miura, Tomihiro
AU  - Miura T
AD  - Department of Internal Medicine, Toho University Omori Medical Center, 
      Omorinishi, Ohta-ku, Tokyo, Japan. t_miura@tobu.saiseikai.or.jp 
      <t_miura@tobu.saiseikai.or.jp>
FAU - Igarashi, Yoshinori
AU  - Igarashi Y
FAU - Okano, Naoki
AU  - Okano N
FAU - Miki, Kazumasa
AU  - Miki K
FAU - Okubo, Yoichiro
AU  - Okubo Y
LA  - eng
PT  - Controlled Clinical Trial
PT  - Journal Article
PL  - Australia
TA  - Dig Endosc
JT  - Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy 
      Society
JID - 9101419
SB  - IM
MH  - Adenocarcinoma/*diagnosis
MH  - Adenoma/*diagnosis
MH  - Aged
MH  - Diagnosis, Differential
MH  - *Endoscopes
MH  - Endoscopy, Digestive System/*instrumentation
MH  - Equipment Design
MH  - Female
MH  - Humans
MH  - Hyperplasia/diagnosis
MH  - Male
MH  - *Pancreatic Ducts
MH  - Pancreatic Neoplasms/*diagnosis
EDAT- 2010/05/08 06:00
MHDA- 2010/09/15 06:00
CRDT- 2010/05/08 06:00
PHST- 2010/05/08 06:00 [entrez]
PHST- 2010/05/08 06:00 [pubmed]
PHST- 2010/09/15 06:00 [medline]
AID - DEN926 [pii]
AID - 10.1111/j.1443-1661.2010.00926.x [doi]
PST - ppublish
SO  - Dig Endosc. 2010 Apr;22(2):119-23. doi: 10.1111/j.1443-1661.2010.00926.x.