PMID- 20448520 OWN - NLM STAT- MEDLINE DCOM- 20100713 LR - 20190923 IS - 1092-8529 (Print) IS - 1092-8529 (Linking) VI - 15 IP - 5 DP - 2010 May TI - Obsessive-compulsive symptom dimensions in Japanese tourette syndrome subjects. PG - 296-303 AB - OBJECTIVES: To investigate the current and lifetime frequency and severity of obsessive-compulsive (OC) symptom dimensions in Tourette syndrome (TS) patients, and how these dimensions affect clinical characteristics. METHODS: Forty TS outpatients (29 males, 11 females) were interviewed with the Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS), the Yale Global Tic Severity Scale (YGTSS), the Shapiro Tourette Syndrome Severity Scale, and the Global Assessment of Functioning (GAF). RESULTS: OC symptoms were present in 80% of the total sample. The miscellaneous and the symmetry dimensions were the most frequent at the "current" and "lifetime" surveys, respectively. The aggression dimension had the smallest difference between "worst ever" and current ratings among the all OC symptom dimensions. TS patients with the aggression dimension (n=7) had significantly lower scores in the GAF scale and higher frequencies of coprolalia. There were significant correlations between the YGTSS severity scores and specific DY-BOCS dimensions. CONCLUSION: OC symptoms are frequent in TS subjects and there were differences in the frequency, severity, and course of the OC symptom dimensions. These results emphasize the need for future longitudinal studies using a dimensional approach for the evaluation of OC symptoms in tic disorders. FAU - Kano, Yukiko AU - Kano Y AD - University of Tokyo Hospital, Japan. kano-tky@umin.ac.jp FAU - Kono, Toshiaki AU - Kono T FAU - Shishikura, Kurie AU - Shishikura K FAU - Konno, Chizue AU - Konno C FAU - Kuwabara, Hitoshi AU - Kuwabara H FAU - Ohta, Masataka AU - Ohta M FAU - do Rosario, Maria Conceicao AU - do Rosario MC LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - CNS Spectr JT - CNS spectrums JID - 9702877 SB - IM MH - Adolescent MH - Adult MH - Chi-Square Distribution MH - Child MH - Diagnosis, Differential MH - Female MH - Humans MH - Japan/epidemiology MH - Male MH - Obsessive-Compulsive Disorder/*diagnosis/*epidemiology MH - Personality Inventory MH - Psychiatric Status Rating Scales MH - Retrospective Studies MH - Severity of Illness Index MH - Tourette Syndrome/*diagnosis/*epidemiology MH - Young Adult EDAT- 2010/05/08 06:00 MHDA- 2010/07/14 06:00 CRDT- 2010/05/08 06:00 PHST- 2010/05/08 06:00 [entrez] PHST- 2010/05/08 06:00 [pubmed] PHST- 2010/07/14 06:00 [medline] AID - 10.1017/s1092852900027528 [doi] PST - ppublish SO - CNS Spectr. 2010 May;15(5):296-303. doi: 10.1017/s1092852900027528.