PMID- 20450060 OWN - NLM STAT- MEDLINE DCOM- 20100525 LR - 20191111 IS - 1001-5302 (Print) IS - 1001-5302 (Linking) VI - 35 IP - 4 DP - 2010 Feb TI - [Research progress on IR improvement and acting mechanisms of active ingredients of traditional Chinese medicine]. PG - 531-5 AB - The insulin resistance (IR) and the active ingredients of traditional Chinese medicine and their mechanisms to improve IR in the last 3 years are summarized. Retrieve, classify and arrange the recent documentations of china and abroad. IR can drive the occurrence and progress of type 2 diabetes mellitus (T2DM), and there are several molecular mechanisms for the occurrence of IR. IR has been a research focus of diabetes, the control strategies of T2DM have been changed from the "hypoglycemic therapy" into "improve the IR and IR-related metabolic abnormalities, and make a comprehensive prevention and treatment of cardiovascular risk factors". It is demonstrated by experiments that a variety of active ingredients of traditional Chinese medicine can improve IR through different mechanisms to treat diabetes mellitus. FAU - Zheng, Hua AU - Zheng H AD - School of Pharmacological Science, Jiangsu University, Zhenjiang 212013, China. zhenghuas08@126.com FAU - Ge, Yanru AU - Ge Y LA - chi PT - English Abstract PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review PL - China TA - Zhongguo Zhong Yao Za Zhi JT - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JID - 8913656 RN - 0 (Drugs, Chinese Herbal) SB - IM MH - Animals MH - Diabetes Mellitus, Type 2/complications/drug therapy/*physiopathology MH - Drugs, Chinese Herbal/*analysis/*therapeutic use MH - Humans MH - *Insulin Resistance MH - *Medicine, Chinese Traditional RF - 32 EDAT- 2010/05/11 06:00 MHDA- 2010/05/26 06:00 CRDT- 2010/05/11 06:00 PHST- 2010/05/11 06:00 [entrez] PHST- 2010/05/11 06:00 [pubmed] PHST- 2010/05/26 06:00 [medline] AID - 10.4268/cjcmm20100428 [doi] PST - ppublish SO - Zhongguo Zhong Yao Za Zhi. 2010 Feb;35(4):531-5. doi: 10.4268/cjcmm20100428.