PMID- 20452283
OWN - NLM
STAT- MEDLINE
DCOM- 20101108
LR  - 20220318
IS  - 1878-1861 (Electronic)
IS  - 1878-1861 (Linking)
VI  - 13
IP  - 4
DP  - 2010 Jul
TI  - Adaptations to skeletal muscle with endurance exercise training in the acutely 
      fed versus overnight-fasted state.
PG  - 465-9
LID - 10.1016/j.jsams.2010.03.002 [doi]
AB  - Minimising carbohydrate (CHO) status in the peri-training period may accelerate 
      the training adaptations normally observed. The aim of this study was to compare 
      adaptations to endurance training undertaken in the acutely CHO fed and 
      overnight-fasted states. Eight female and six male untrained, healthy 
      participants: aged 26.6+/-5.8 years (mean+/-SD); height 174.7+/-7.6 cm; weight 
      75.3+/-11.4 kg; VO(2max) 3.48+/-0.67 l/min; were randomly divided into two 
      training groups and undertook four weeks of five days per week endurance cycle 
      ergometer training in either the overnight-fasted (FAST) or acutely fed (FED) 
      state. FAST training had no effect on RER or plasma glucose, lactate and FFA 
      concentrations during subsequent submaximal exercise. Training-induced changes in 
      Vastus lateralis citrate synthase (CS) and 3-hydroxy-CoA dehydrogenase (HAD) 
      activities were not different between training groups (P=0.655 and 0.549, 
      respectively), but when the effect of gender was considered, men responded better 
      to FAST and women responded better to FED. The FAST group showed a significantly 
      greater training-induced increase in VO(2max) and resting muscle glycogen 
      concentration than FED (P=0.014 and P=0.047 respectively), but there was no 
      gender interaction. In conclusion, these results suggest that (a) meal ingestion 
      prior to daily exercise can modify some of the exercise training-induced 
      adaptations normally seen with endurance training compared to when daily exercise 
      is undertaken in the overnight-fasted state; and (b) the extent of these 
      adaptations in skeletal muscle differ slightly between men and women.
CI  - Copyright 2010 Sports Medicine Australia. All rights reserved.
FAU - Stannard, Stephen R
AU  - Stannard SR
AD  - Institute of Food Nutrition and Human Health, Massey University, Palmerston 
      North, New Zealand. S.Stannard@massey.ac.nz
FAU - Buckley, Alex J
AU  - Buckley AJ
FAU - Edge, Johann A
AU  - Edge JA
FAU - Thompson, Martin W
AU  - Thompson MW
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20100507
PL  - Australia
TA  - J Sci Med Sport
JT  - Journal of science and medicine in sport
JID - 9812598
RN  - 9005-79-2 (Glycogen)
RN  - EC 2.3.3.1 (Citrate (si)-Synthase)
SB  - IM
MH  - Adaptation, Physiological/*physiology
MH  - Adult
MH  - Citrate (si)-Synthase/metabolism
MH  - Fasting/*physiology
MH  - Female
MH  - Glycogen/metabolism
MH  - Humans
MH  - Male
MH  - Muscle, Skeletal/*physiology
MH  - Oxygen Consumption
MH  - Physical Endurance/*physiology
MH  - Young Adult
EDAT- 2010/05/11 06:00
MHDA- 2010/11/09 06:00
CRDT- 2010/05/11 06:00
PHST- 2009/02/11 00:00 [received]
PHST- 2009/12/21 00:00 [revised]
PHST- 2010/03/17 00:00 [accepted]
PHST- 2010/05/11 06:00 [entrez]
PHST- 2010/05/11 06:00 [pubmed]
PHST- 2010/11/09 06:00 [medline]
AID - S1440-2440(10)00073-3 [pii]
AID - 10.1016/j.jsams.2010.03.002 [doi]
PST - ppublish
SO  - J Sci Med Sport. 2010 Jul;13(4):465-9. doi: 10.1016/j.jsams.2010.03.002. Epub 
      2010 May 7.