PMID- 20459489
OWN - NLM
STAT- MEDLINE
DCOM- 20101130
LR  - 20110425
IS  - 1532-950X (Electronic)
IS  - 0161-3499 (Linking)
VI  - 39
IP  - 6
DP  - 2010 Aug
TI  - Open heart surgery with deep hypothermia and cardiopulmonary bypass in small and 
      toy dogs.
PG  - 674-9
LID - 10.1111/j.1532-950X.2010.00687.x [doi]
AB  - OBJECTIVE: To evaluate open heart surgery with deep surface-induced hypothermia 
      (sHT) and low-flow cardiopulmonary bypass (CPB) in small and toy-breed dogs. 
      STUDY DESIGN: Case series. ANIMALS: Small breed dogs (n=8) weighing <5.5 kg with 
      naturally occurring cardiac disease. METHODS: Deep sHT under isoflurane 
      anesthesia and low-flow rate CPB with a small-volume prime circuit were used. 
      Ventricular septal defect was closed directly in 2 dogs and severe mitral 
      regurgitation was corrected with mitral valvuloplasty (MVP) in 5 dogs and mitral 
      valve replacement in 1 dog. RESULTS: All dogs survived surgery; 1 dog died 6 days 
      and 1 died 2 months after MVP. The other 6 dogs lived (mean follow-up, 32.8 
      months; range, 12-65 months). Mean body weight at surgery was 3.6 kg (range, 
      2-5.3 kg). Mean lowest esophageal temperature was 21.4 degrees C (range, 
      19.8-23.8 degrees C). Mean lowest pump flow volume was 29.2 mL/kg/min (range, 
      9.4-57.7 mL/kg/min) during aortic cross-clamping (mean, 53.5 minutes; range, 
      25-79 minutes). Mean hematocrit before CPB was 38.6% (range, 33-47%) and 20.3% 
      (range, 13-24%) during CPB with a small circuit priming volume of 225-260 mL. 
      CONCLUSION: Deep sHT with low-flow rate CPB may be used for open heart surgery in 
      small dogs weighing <5.5 kg. CLINICAL RELEVANCE: Open heart surgery for selected 
      congenital defects and acquired defects in small and toy-breed dogs may be 
      successfully performed using deep sHT and CPB.
FAU - Kanemoto, Isamu
AU  - Kanemoto I
AD  - Chayagasaka Animal Hospital, Nagoya, Japan. kanemoto@ta2.so-net.ne.jp
FAU - Taguchi, Daisuke
AU  - Taguchi D
FAU - Yokoyama, Satoko
AU  - Yokoyama S
FAU - Mizuno, Masashi
AU  - Mizuno M
FAU - Suzuki, Hiromi
AU  - Suzuki H
FAU - Kanamoto, Tougaku
AU  - Kanamoto T
LA  - eng
PT  - Journal Article
DEP - 20100429
PL  - United States
TA  - Vet Surg
JT  - Veterinary surgery : VS
JID - 8113214
SB  - IM
MH  - Animals
MH  - Breeding
MH  - Cardiopulmonary Bypass/methods/*veterinary
MH  - Dog Diseases/mortality/*surgery
MH  - Dogs
MH  - Heart Diseases/mortality/surgery/*veterinary
MH  - Hypothermia, Induced/*veterinary
MH  - Male
MH  - Postoperative Complications/veterinary
MH  - Survival Analysis
MH  - Treatment Outcome
EDAT- 2010/05/13 06:00
MHDA- 2010/12/14 06:00
CRDT- 2010/05/13 06:00
PHST- 2010/05/13 06:00 [entrez]
PHST- 2010/05/13 06:00 [pubmed]
PHST- 2010/12/14 06:00 [medline]
AID - VSU00687 [pii]
AID - 10.1111/j.1532-950X.2010.00687.x [doi]
PST - ppublish
SO  - Vet Surg. 2010 Aug;39(6):674-9. doi: 10.1111/j.1532-950X.2010.00687.x. Epub 2010 
      Apr 29.