PMID- 20467314 OWN - NLM STAT- MEDLINE DCOM- 20100813 LR - 20100615 IS - 1531-7021 (Electronic) IS - 1040-8738 (Linking) VI - 21 IP - 4 DP - 2010 Jul TI - Refractive surgery after corneal transplant. PG - 259-64 LID - 10.1097/ICU.0b013e32833a9abb [doi] AB - PURPOSE OF REVIEW: Ametropia and astigmatism following successful penetrating keratoplasty can seriously impact a patient's quality of vision. Similar limitations can result following anterior lamellar keratoplasty (ALK) and Descemet's stripping endothelial keratoplasty (DSEK). These patients often suffer from aniseikonia and can be intolerant of spectacles and contact lenses. Refractive surgery can correct both ametropia and astigmatism following corneal transplantation and improve a patient's final visual outcome. The same methods used to correct naturally occurring refractive errors are being used with increasing success in patients who have undergone corneal transplants. RECENT FINDINGS: Many refractive options are available to treat ametropia following penetrating keratoplasty. Incisional keratotomies have been employed to treat high amounts of astigmatism. Photorefractive keratectomy (PRK) and laser in-situ keratomileusis (LASIK) are also used to treat myopia, hyperopia and astigmatism. LASIK has been shown to have an overall better outcome compared to PRK; however, the use of mitomycin-C with PRK has improved results. Phakic and pseudophakic piggyback intraocular lenses are also being used to treat high degrees of ametropia and astigmatism; however, the long-term results are somewhat limited. SUMMARY: Refractive surgery can improve the final visual outcome of patients who have undergone successful corneal transplantation. Currently available modalities provide many options for patients who are intolerant of spectacles and contact lenses. Continued advances and research will enable surgeons to optimize visual quality in postkeratoplasty patients. FAU - Kuryan, Jocelyn AU - Kuryan J AD - Department of Ophthalmology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York 10467, USA. FAU - Channa, Prabjot AU - Channa P LA - eng PT - Journal Article PT - Review PL - United States TA - Curr Opin Ophthalmol JT - Current opinion in ophthalmology JID - 9011108 SB - IM MH - *Corneal Transplantation MH - Humans MH - *Postoperative Care MH - *Refractive Surgical Procedures RF - 78 EDAT- 2010/05/15 06:00 MHDA- 2010/08/14 06:00 CRDT- 2010/05/15 06:00 PHST- 2010/05/15 06:00 [entrez] PHST- 2010/05/15 06:00 [pubmed] PHST- 2010/08/14 06:00 [medline] AID - 10.1097/ICU.0b013e32833a9abb [doi] PST - ppublish SO - Curr Opin Ophthalmol. 2010 Jul;21(4):259-64. doi: 10.1097/ICU.0b013e32833a9abb.