PMID- 2048393 OWN - NLM STAT- MEDLINE DCOM- 19910716 LR - 20190814 IS - 0001-6314 (Print) IS - 0001-6314 (Linking) VI - 83 IP - 4 DP - 1991 Apr TI - Does the variability of casual blood pressure contribute to progressive subcortical vascular encephalopathy of Binswanger's type? PG - 209-13 AB - Our hypothesis was that progressive subcortical vascular encephalopathy of Binswanger's type (PSVE) in the elderly can be induced by repeated hypotension or greater variability of blood pressure in hypertensives, regardless of antihypertensive therapy. We retrospectively studied PSVE blood pressure, and compared them with those in atherothrombotic cerebral infarction (ACI) or in hypertensive cerebral hemorrhage (HCH). During the last seven years prior to death, neither the annual variability nor the annual mean value of systolic or mean arterial blood pressures in PSVE was different from that in ACI or in HCH. The present study did not support our hypothesis. FAU - Yamanouchi, H AU - Yamanouchi H AD - Department of Neurology, Tokyo Metropolitan Geriatric Hospital, Japan. FAU - Ueda, K AU - Ueda K FAU - Shimada, H AU - Shimada H FAU - Kuramoto, K AU - Kuramoto K FAU - Toyokura, Y AU - Toyokura Y LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Denmark TA - Acta Neurol Scand JT - Acta neurologica Scandinavica JID - 0370336 SB - IM MH - Aged MH - Aged, 80 and over MH - *Blood Pressure MH - Cerebral Infarction/etiology/*physiopathology MH - Female MH - Homes for the Aged MH - Humans MH - Hypertension/complications/drug therapy MH - Hypotension/complications MH - Intracranial Arteriosclerosis/*physiopathology MH - Intracranial Embolism and Thrombosis/*physiopathology MH - Male MH - Nursing Homes MH - Retrospective Studies EDAT- 1991/04/01 00:00 MHDA- 1991/04/01 00:01 CRDT- 1991/04/01 00:00 PHST- 1991/04/01 00:00 [pubmed] PHST- 1991/04/01 00:01 [medline] PHST- 1991/04/01 00:00 [entrez] AID - 10.1111/j.1600-0404.1991.tb04684.x [doi] PST - ppublish SO - Acta Neurol Scand. 1991 Apr;83(4):209-13. doi: 10.1111/j.1600-0404.1991.tb04684.x.