PMID- 20491705 OWN - NLM STAT- MEDLINE DCOM- 20110308 LR - 20220310 IS - 1651-2227 (Electronic) IS - 0803-5253 (Linking) VI - 99 IP - 10 DP - 2010 Oct TI - Serum albumin level predicts initial intravenous immunoglobulin treatment failure in Kawasaki disease. PG - 1578-83 LID - 10.1111/j.1651-2227.2010.01875.x [doi] AB - OBJECTIVES: Kawasaki disease (KD) is a systemic vasculitis primarily affecting children who are <5 years old. Intravenous immunoglobulin (IVIG) is the standard therapy for KD. However, many patients with KD still show poor response to initial IVIG treatment. This study was conducted to investigate the risk factors for initial IVIG treatment failure in KD. METHODS: Children who met KD diagnosis criteria and were admitted for IVIG treatment were retrospectively enrolled for analysis. Patients were divided into IVIG-responsive and IVIG-resistant groups. Initial laboratory data before IVIG treatment were collected for analysis. RESULTS: A total of 131 patients were enrolled during the study period. At 48 h after completion of initial IVIG treatment, 20 patients (15.3%) had an elevated body temperature. Univariate analysis showed that patients who had initial findings of high neutrophil count, abnormal liver function, low serum albumin level (