PMID- 20492599
OWN - NLM
STAT- MEDLINE
DCOM- 20101203
LR  - 20221207
IS  - 1399-0039 (Electronic)
IS  - 0001-2815 (Linking)
VI  - 76
IP  - 3
DP  - 2010 Sep
TI  - Correlation between genetic HLA class I and II polymorphisms and anthropological 
      aspects in the Chaouya population from Morocco (Arabic speaking).
PG  - 177-93
LID - 10.1111/j.1399-0039.2010.01498.x [doi]
AB  - The aim of this study was to provide genetic and anthropological information on 
      the Chaouya (CH), an Arabic-speaking population living in West Morocco, Atlantic 
      coast (Settat). In 98 unrelated healthy CH volunteers, we first investigated the 
      human leukocyte antigen (HLA) class I and II allele polymorphisms using a 
      sequence-based typing method and examined haplotypes and relatedness of this 
      group to other African and Mediterranean populations. The study showed the close 
      relatedness with Tunisian population and other North Africans, together with a 
      strong influence of various immigrations, mainly Spaniards, French, and 
      Portuguese, as expected. Nevertheless, analysis of class II allele frequencies 
      (afs) showed that Oromo and Amhara Ethiopian groups cluster together with the 
      Berbers and other North Africans, confirming the relationship between these 
      populations (Afro-Asiatic linguistic group, Hamites). South and sub-Saharan 
      Africans cluster separately at a great distance from CH, except the sub-Saharan 
      Bantu population from Congo Kinshasa, which shows a relatively close genetic 
      relationship ascribable to the effect of a diversifying selection. On the other 
      hand, considering HLA class I afs analyses, it was noteworthy that CH grouped 
      together with sub-Saharans, showing a close genetic distance mainly with Ugandas 
      and Kenians Luo.
FAU - Canossi, A
AU  - Canossi A
AD  - CNR Institute Organ Transplants and Immunocitology, L'Aquila, Italy. 
      angelica.canossi@cnr.it
FAU - Piancatelli, D
AU  - Piancatelli D
FAU - Aureli, A
AU  - Aureli A
FAU - Oumhani, K
AU  - Oumhani K
FAU - Ozzella, G
AU  - Ozzella G
FAU - Del Beato, T
AU  - Del Beato T
FAU - Liberatore, G
AU  - Liberatore G
FAU - El Aouad, R
AU  - El Aouad R
FAU - Adorno, D
AU  - Adorno D
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Tissue Antigens
JT  - Tissue antigens
JID - 0331072
RN  - 0 (Histocompatibility Antigens Class I)
RN  - 0 (Histocompatibility Antigens Class II)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Alleles
MH  - Anthropology, Physical
MH  - Black People/*genetics
MH  - Female
MH  - Gene Frequency
MH  - Haplotypes/genetics
MH  - Histocompatibility Antigens Class I/*genetics
MH  - Histocompatibility Antigens Class II/*genetics
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Morocco/epidemiology
MH  - Phylogeny
MH  - Polymorphism, Genetic/*genetics
EDAT- 2010/05/25 06:00
MHDA- 2010/12/14 06:00
CRDT- 2010/05/25 06:00
PHST- 2010/05/25 06:00 [entrez]
PHST- 2010/05/25 06:00 [pubmed]
PHST- 2010/12/14 06:00 [medline]
AID - TAN1498 [pii]
AID - 10.1111/j.1399-0039.2010.01498.x [doi]
PST - ppublish
SO  - Tissue Antigens. 2010 Sep;76(3):177-93. doi: 10.1111/j.1399-0039.2010.01498.x.