PMID- 20494668
OWN - NLM
STAT- MEDLINE
DCOM- 20100708
LR  - 20151119
IS  - 1879-1913 (Electronic)
IS  - 0002-9149 (Linking)
VI  - 105
IP  - 11
DP  - 2010 Jun 1
TI  - Significance of magnetic resonance imaging in apical hypertrophic cardiomyopathy.
PG  - 1592-6
LID - 10.1016/j.amjcard.2010.01.020 [doi]
AB  - Apical hypertrophic cardiomyopathy (HC) is an uncommon variant of nonobstructive 
      HC with peculiar characteristics. The investigators report a series of 13 
      consecutive Caucasian patients with a suspicion or diagnosis of apical HC on the 
      basis of electrocardiographic and/or echocardiographic findings who prospectively 
      underwent magnetic resonance imaging with late gadolinium enhancement (LGE) 
      evaluation. All but 1 patient presented T-wave inversion in the anterolateral 
      leads on electrocardiogram, with a mean maximum negative T wave of 7.0 +/- 3.9 
      mm. Echocardiography provided correct diagnoses in 9/13 patients (69%), while in 
      4 patients echocardiographic results were normal or inconclusive. Magnetic 
      resonance imaging showed a spadelike morphology of the left ventricle in 6 
      patients and identified an apical aneurysm in 4. Eleven patients (85%) presented 
      LGE with a mean percentage of 2.3 +/- 2.6% of total left ventricular mass. In 9 
      (69%) patients LGE was limited to the hypertrophic segments while in 6 (46%) 
      patients it was also present in nonhypertrophic segments. In conclusion, magnetic 
      resonance imaging in patients with apical HC showed a high incidence of apical 
      aneurysms and a peculiar distribution of LGE, that was not limited to 
      hypertrophic segments.
CI  - Copyright 2010 Elsevier Inc. All rights reserved.
FAU - Fattori, Rossella
AU  - Fattori R
AD  - Institute of Cardiovascular Radiology, S. Orsola-Malpighi University Hospital, 
      Bologna, Italy. rossella.fattori@unibo.it
FAU - Biagini, Elena
AU  - Biagini E
FAU - Lorenzini, Massimiliano
AU  - Lorenzini M
FAU - Buttazzi, Katia
AU  - Buttazzi K
FAU - Lovato, Luigi
AU  - Lovato L
FAU - Rapezzi, Claudio
AU  - Rapezzi C
LA  - eng
PT  - Journal Article
DEP - 20100410
PL  - United States
TA  - Am J Cardiol
JT  - The American journal of cardiology
JID - 0207277
RN  - 0 (Contrast Media)
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cardiomyopathy, Hypertrophic/*diagnosis/epidemiology
MH  - *Contrast Media
MH  - *Electrocardiography
MH  - Female
MH  - *Gadolinium
MH  - Heart Aneurysm/diagnosis
MH  - Heart Ventricles/*pathology
MH  - Humans
MH  - Image Interpretation, Computer-Assisted
MH  - Incidence
MH  - Italy/epidemiology
MH  - *Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Sensitivity and Specificity
MH  - Severity of Illness Index
EDAT- 2010/05/25 06:00
MHDA- 2010/07/09 06:00
CRDT- 2010/05/25 06:00
PHST- 2009/11/21 00:00 [received]
PHST- 2010/01/05 00:00 [revised]
PHST- 2010/01/05 00:00 [accepted]
PHST- 2010/05/25 06:00 [entrez]
PHST- 2010/05/25 06:00 [pubmed]
PHST- 2010/07/09 06:00 [medline]
AID - S0002-9149(10)00106-2 [pii]
AID - 10.1016/j.amjcard.2010.01.020 [doi]
PST - ppublish
SO  - Am J Cardiol. 2010 Jun 1;105(11):1592-6. doi: 10.1016/j.amjcard.2010.01.020. Epub 
      2010 Apr 10.