PMID- 20504123 OWN - NLM STAT- MEDLINE DCOM- 20100913 LR - 20100527 IS - 1525-6006 (Electronic) IS - 1064-1963 (Linking) VI - 32 IP - 3 DP - 2010 May TI - Increased risk of pre-eclampsia (PE) among women with the history of migraine. PG - 159-65 LID - 10.3109/10641960903254489 [doi] AB - The Objective of this study was to assess possible association of history of migraine with pre-eclampsia (PE). This was a retrospective study to compare history of migraine in 90 women affected by PE with 90 women without PE as the control group. They recruited by a nonrandomized consecutive sampling method. Data were collected by a questionnaire including demographic, medical, obstetrics, and migraine assessment sections. Data were analyzed using SPSS. Results showed an increased risk of PE in women with history of migraine (odds ratio: 2.87; p < 0.05). Result demonstrated that migraine history in the case group is 14/4% and in control group is 5/6%. Gestational age (GA) at delivery and weight of neonate (WN) were significantly lower compared to control (GA: 37.3 +/- 2.6 vs. 38.7+/- 1.3 weeks T test; P < 0.01) (WN: 2930 +/- 690 vs. 3330 +/- 420; T test; P < 0.0). Cesarean section was more frequent in the PE group compared to the control group [37 (42%) vs. 14 (15.6%)]; chi square; p < 0.01]. The association of migraine with PE is the result of some similar mechanism leading to endothelial dysfunction. Frequent reports of an association between migraine and PE in different populations suggest a history of migraine as a risk factor for PE/gestational hypertension (GH). FAU - Simbar, Masoumeh AU - Simbar M AD - Department of Reproductive Health and Midwifery, Shahid Beheshti Medical Science University, Tehran, Iran. msimbar@sbmu.ac.ir FAU - Karimian, Zahra AU - Karimian Z FAU - Afrakhteh, Maryam AU - Afrakhteh M FAU - Akbarzadeh, Alireza AU - Akbarzadeh A FAU - Kouchaki, Ebrahim AU - Kouchaki E LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Clin Exp Hypertens JT - Clinical and experimental hypertension (New York, N.Y. : 1993) JID - 9305929 SB - IM MH - Adult MH - Case-Control Studies MH - Female MH - Gestational Age MH - Humans MH - Infant, Newborn MH - Iran/epidemiology MH - Migraine Disorders/*complications/epidemiology MH - Pre-Eclampsia/epidemiology/*physiopathology MH - Pregnancy MH - Retrospective Studies MH - Risk Factors MH - Young Adult EDAT- 2010/05/28 06:00 MHDA- 2010/09/14 06:00 CRDT- 2010/05/28 06:00 PHST- 2010/05/28 06:00 [entrez] PHST- 2010/05/28 06:00 [pubmed] PHST- 2010/09/14 06:00 [medline] AID - 10.3109/10641960903254489 [doi] PST - ppublish SO - Clin Exp Hypertens. 2010 May;32(3):159-65. doi: 10.3109/10641960903254489.