PMID- 20510715 OWN - NLM STAT- MEDLINE DCOM- 20100915 LR - 20220408 IS - 1557-8259 (Electronic) IS - 0030-6665 (Linking) VI - 43 IP - 2 DP - 2010 Apr TI - Surgical management of cervical lymph nodes in differentiated thyroid cancer. PG - 285-300, viii LID - 10.1016/j.otc.2010.01.005 [doi] AB - Well-differentiated thyroid cancer (DTC) carries an excellent prognosis. Although long-term survival rates are high, regional lymph node metastases are common. Surgical management of cervical lymph nodes is integral to the comprehensive treatment of DTC, but data from large randomized trials do not exist to define optimal treatment. Therapy is thus guided by observational data, and founded on an understanding of the behavior of lymphatic metastases in DTC. This article focuses on the significance of lymph node metastases in thyroid cancer, and the strategy for surgical management. CI - Copyright 2010 Elsevier Inc. All rights reserved. FAU - Fritze, Danielle AU - Fritze D AD - Department of Surgery, University of Michigan, Ann Arbor, MI 48109, USA. FAU - Doherty, Gerard M AU - Doherty GM LA - eng PT - Journal Article PT - Review PL - United States TA - Otolaryngol Clin North Am JT - Otolaryngologic clinics of North America JID - 0144042 SB - IM MH - Adenocarcinoma, Follicular/mortality/pathology/*surgery MH - Carcinoma, Papillary/mortality/pathology/*surgery MH - Disease Progression MH - Humans MH - Lymph Node Excision/*methods MH - Lymph Nodes/pathology MH - Lymphatic Metastasis/*pathology MH - Neck Dissection/methods MH - Neoplasm Invasiveness MH - Neoplasm Staging MH - Practice Guidelines as Topic MH - SEER Program MH - Survival Rate MH - Thyroid Neoplasms/mortality/pathology/*surgery MH - Thyroidectomy/methods RF - 62 EDAT- 2010/06/01 06:00 MHDA- 2010/09/16 06:00 CRDT- 2010/06/01 06:00 PHST- 2010/06/01 06:00 [entrez] PHST- 2010/06/01 06:00 [pubmed] PHST- 2010/09/16 06:00 [medline] AID - S0030-6665(10)00017-4 [pii] AID - 10.1016/j.otc.2010.01.005 [doi] PST - ppublish SO - Otolaryngol Clin North Am. 2010 Apr;43(2):285-300, viii. doi: 10.1016/j.otc.2010.01.005.