PMID- 20518898
OWN - NLM
STAT- MEDLINE
DCOM- 20100902
LR  - 20171116
IS  - 1440-1827 (Electronic)
IS  - 1320-5463 (Linking)
VI  - 60
IP  - 6
DP  - 2010 Jun
TI  - Regression of rectal mucosa-associated lymphoid tissue (MALT) lymphoma after 
      antibiotic treatments.
PG  - 438-42
LID - 10.1111/j.1440-1827.2010.02538.x [doi]
AB  - Only a few reports have described regression of rectal mucosa-associated lymphoid 
      tissue (MALT) lymphoma after antibiotic treatment are generally found to be 
      successful for gastric tumors. We examined eight rectal MALT lymphomas treated 
      with antibiotic treatments to determine whether they regressed after treatment. 
      We also discuss the relationship between rectal MALT lymphomas and MALT1 gene 
      genetic abnormalities. Eight patients who had undergone antibiotic treatments 
      were followed up with colonoscopy after initiation of the treatment. In five of 
      the eight cases (63%) endoscopic examination showed that the rectal tumor had 
      disappeared, which was confirmed histologically. Polymerase chain reaction for 
      immunoglobulin heavy chain identified a monoclonal band in seven of eight cases 
      (88%). Of the eight cases analyzed with fluorescence in situ hybridization (FISH) 
      for MALT1 translocation, two demonstrated MALT1 gene genetic abnormality. These 
      cases tended to be resistant to antibiotic treatment. Investigation and analysis 
      of a large number of rectal MALT lymphomas are needed to establish suitable 
      standards for antibiotic treatment.
FAU - Niino, Daisuke
AU  - Niino D
AD  - Department of Pathology, School of Medicine, Kurume University, Asahi-machi, 
      Kurume, Japan. niino_daisuke@med.kurumeu.ac.jp
FAU - Yamamoto, Kouhei
AU  - Yamamoto K
FAU - Tsuruta, Osamu
AU  - Tsuruta O
FAU - Maeda, Tomoharu
AU  - Maeda T
FAU - Yakushijin, Yoshihiro
AU  - Yakushijin Y
FAU - Aoki, Ryosuke
AU  - Aoki R
FAU - Kimura, Yoshizo
AU  - Kimura Y
FAU - Hashikawa, Keiko
AU  - Hashikawa K
FAU - Kiyasu, Junichi
AU  - Kiyasu J
FAU - Takeuchi, Masanori
AU  - Takeuchi M
FAU - Sugita, Yasuo
AU  - Sugita Y
FAU - Ohshima, Koichi
AU  - Ohshima K
LA  - eng
PT  - Journal Article
PL  - Australia
TA  - Pathol Int
JT  - Pathology international
JID - 9431380
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Antineoplastic Agents)
RN  - 0 (Immunoglobulin Heavy Chains)
RN  - 0 (Neoplasm Proteins)
RN  - EC 3.4.22.- (Caspases)
RN  - EC 3.4.22.- (MALT1 protein, human)
RN  - EC 3.4.22.- (Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Anti-Bacterial Agents/pharmacology/*therapeutic use
MH  - Antineoplastic Agents/pharmacology/*therapeutic use
MH  - Caspases/*genetics
MH  - Colonoscopy
MH  - Drug Resistance, Neoplasm/drug effects/genetics/immunology
MH  - Female
MH  - Gene Rearrangement
MH  - Humans
MH  - Immunoglobulin Heavy Chains/analysis/genetics
MH  - In Situ Hybridization, Fluorescence
MH  - Lymphoma, B-Cell, Marginal Zone/*drug therapy/genetics/pathology
MH  - Male
MH  - Middle Aged
MH  - Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
MH  - Neoplasm Proteins/*genetics
MH  - Rectal Neoplasms/*drug therapy/genetics/pathology
MH  - Remission Induction
MH  - Translocation, Genetic
EDAT- 2010/06/04 06:00
MHDA- 2010/09/03 06:00
CRDT- 2010/06/04 06:00
PHST- 2010/06/04 06:00 [entrez]
PHST- 2010/06/04 06:00 [pubmed]
PHST- 2010/09/03 06:00 [medline]
AID - PIN2538 [pii]
AID - 10.1111/j.1440-1827.2010.02538.x [doi]
PST - ppublish
SO  - Pathol Int. 2010 Jun;60(6):438-42. doi: 10.1111/j.1440-1827.2010.02538.x.