PMID- 20523361
OWN - NLM
STAT- MEDLINE
DCOM- 20110726
LR  - 20220310
IS  - 1476-5454 (Electronic)
IS  - 0950-222X (Linking)
VI  - 24
IP  - 10
DP  - 2010 Oct
TI  - Vitreous traction and epiretinal membranes in diabetic macular oedema using 
      spectral-domain optical coherence tomography.
PG  - 1545-53
LID - 10.1038/eye.2010.80 [doi]
AB  - PURPOSE: The purpose of this study was to present an association between diabetic 
      macular oedema (DME) and vitreoretinal interface abnormalities using 3D spectral 
      domain optical coherence tomography (SD-OCT). METHODS: In a retrospective study, 
      charts and SD-OCT of consecutive patients with diffuse or focal DME were 
      reviewed. Only one randomly chosen eye per patient with DME was included, and 
      eyes that had another retinopathy that could affect the study analysis or that 
      underwent vitreoretinal surgery were excluded. RESULTS: Out of 58 eyes (58 
      patients) with DME, 11 eyes (19.0%) had vitreofoveal traction (Group A), either 
      unifocally (n=6) or multifocally; that is, associated with additional extrafoveal 
      traction site(s). Group B comprised 20 eyes (34.5%) that had sole extrafoveal 
      vitreous traction, at either retinal and/or papillary sites. In each, the retinal 
      oedema underlying extrafoveal traction was in continuum in at least one site with 
      that at the central macula, as verified by the macular maps, thus presented as 
      diffuse macular oedema. In Group C, 13 eyes (22.4%) had an epiretinal membrane 
      (ERM), 1.5 x 3 mm to >/=6 x 6 mm in size that overlaid diffuse oedematous macula. 
      Group D included 14 eyes (24.1%) that had neither vitreous traction nor ERM; 12 
      (20.7%) of them had DME secondary to leaking microaneurysms with or without 
      leaking capillary beds, and the remaining two had leakage from non-microaneurysms 
      sources. CONCLUSIONS: DME was detected by the SD-OCT to be associated with sole 
      extrafoveal vitreous traction in one-third of the patients. Further studies are 
      required to evaluate the clinical consequences of these observations.
FAU - Ophir, A
AU  - Ophir A
AD  - Division of Ophthalmology, Hillel-Yaffe Medical Centre, Hadera, Israel. 
      ophthalmology@hy.health.gov.il
FAU - Martinez, M R
AU  - Martinez MR
FAU - Mosqueda, P
AU  - Mosqueda P
FAU - Trevino, A
AU  - Trevino A
LA  - eng
PT  - Journal Article
DEP - 20100604
PL  - England
TA  - Eye (Lond)
JT  - Eye (London, England)
JID - 8703986
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Diabetic Retinopathy/*complications
MH  - Epiretinal Membrane/*diagnosis
MH  - Female
MH  - Humans
MH  - Macula Lutea/pathology
MH  - Macular Edema/*complications/pathology
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Tomography, Optical Coherence/methods
MH  - Vitreous Detachment/*diagnosis
EDAT- 2010/06/05 06:00
MHDA- 2011/07/27 06:00
CRDT- 2010/06/05 06:00
PHST- 2010/06/05 06:00 [entrez]
PHST- 2010/06/05 06:00 [pubmed]
PHST- 2011/07/27 06:00 [medline]
AID - eye201080 [pii]
AID - 10.1038/eye.2010.80 [doi]
PST - ppublish
SO  - Eye (Lond). 2010 Oct;24(10):1545-53. doi: 10.1038/eye.2010.80. Epub 2010 Jun 4.