PMID- 20525161 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20121002 LR - 20211020 IS - 1710-1492 (Electronic) IS - 1710-1484 (Print) IS - 1710-1484 (Linking) VI - 2 IP - 2 DP - 2006 Jun 15 TI - Nonimmunoglobulin e-mediated immune reactions to foods. PG - 78-85 LID - 10.1186/1710-1492-2-2-78 [doi] AB - : Adverse food reactions are abnormal responses to ingested foods. Reactions vary from immunologic to nonimmunologic immune reactions and can be either immunoglobulin E (IgE) mediated or non-IgE mediated. Food-induced IgE-mediated reactions range from localized urticaria to anaphylaxis and have been well studied. However, in comparison, there has been significantly less research into non-IgE-mediated food reactions. Non-IgE-mediated reactions can cause respiratory, gastrointestinal, and cutaneous symptoms. The most recent evidence suggests that these reactions are probably T-cell mediated as evidenced in lymphocyte proliferation assays. This review will explore the symptoms and testing methods of the most common non-IgE-mediated reactions. FAU - Spergel, Jonathan M AU - Spergel JM AD - Assistant Professor of Pediatrics, Division of Allergy and Immunology, Department of Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania. spergel@email.chop.edu. LA - eng PT - Journal Article DEP - 20060615 PL - England TA - Allergy Asthma Clin Immunol JT - Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology JID - 101244313 PMC - PMC2876187 EDAT- 2006/06/15 00:00 MHDA- 2006/06/15 00:01 PMCR- 2006/06/15 CRDT- 2010/06/08 06:00 PHST- 2010/06/08 06:00 [entrez] PHST- 2006/06/15 00:00 [pubmed] PHST- 2006/06/15 00:01 [medline] PHST- 2006/06/15 00:00 [pmc-release] AID - 1710-1492-2-2-78 [pii] AID - 10.1186/1710-1492-2-2-78 [doi] PST - ppublish SO - Allergy Asthma Clin Immunol. 2006 Jun 15;2(2):78-85. doi: 10.1186/1710-1492-2-2-78. Epub 2006 Jun 15.