PMID- 20529154
OWN - NLM
STAT- MEDLINE
DCOM- 20110621
LR  - 20100720
IS  - 1540-8191 (Electronic)
IS  - 0886-0440 (Linking)
VI  - 25
IP  - 4
DP  - 2010 Jul
TI  - Safety and efficacy of arterial switch operation in previously inoperable 
      patients.
PG  - 400-5
LID - 10.1111/j.1540-8191.2010.01070.x [doi]
AB  - BACKGROUND: Patients older than six months with complete transposition of the 
      great arteries and ventricular septal defect or Taussig-Bing anomaly and severe 
      pulmonary arterial hypertension (PAH), previously thought to be inoperable, 
      usually are not indicated for arterial switch operation (ASO) or even repair. 
      This study aimed to evaluate the safety and efficacy of ASO in these selected 
      subset patients. METHODS: The records of 86 patients older than six months with 
      complete transposition of the great arteries and ventricular septal defect or 
      Taussig-Bing anomaly and severe PAH who underwent ASO at our institution from May 
      2000 to October 2008 were reviewed retrospectively. Eighty survivors were 
      followed-up. RESULTS: There were six hospital deaths (7.0%, 95% confidence limit 
      1.6 to 12.4%). From January 2006 to October 2008, 46 consecutive ASOs were 
      performed with no death. Operative mortality and mobility decreased significantly 
      (p = 0.008 and p = 0.046, respectively). The median duration of follow-up was 
      42.1 +/- 28.8 months (range, 2.0 to 99.5). Two late deaths occurred. Latest 
      follow-up data showed that 2.8% of survivors were in New York Heart Association 
      (NYHA) class II and 97.2% were in NYHA class I. CONCLUSIONS: Excellent early and 
      mid-term results of ASO are obtained from patients older than six months with 
      complete transposition of the great arteries and ventricular septal defect or 
      Taussig-Bing anomaly and severe PAH in current era, and ASO is safe and effective 
      in these selected subset patients.
FAU - Liu, Ying-Long
AU  - Liu YL
AD  - Pediatric Cardiac Center, Cardiovascular Institute and Fuwai Hospital, Chinese 
      Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
FAU - Hu, Sheng-Shou
AU  - Hu SS
FAU - Shen, Xiang-Dong
AU  - Shen XD
FAU - Li, Shou-Jun
AU  - Li SJ
FAU - Wang, Xu
AU  - Wang X
FAU - Yan, Jun
AU  - Yan J
FAU - Wu, Xin
AU  - Wu X
FAU - Huang, Jing-Bin
AU  - Huang JB
FAU - Kong, Bo
AU  - Kong B
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20100530
PL  - United States
TA  - J Card Surg
JT  - Journal of cardiac surgery
JID - 8908809
SB  - IM
MH  - Adolescent
MH  - Cardiac Surgical Procedures/adverse effects/instrumentation/*methods
MH  - Child
MH  - Child, Preschool
MH  - China
MH  - Confidence Intervals
MH  - Double Outlet Right Ventricle/*surgery
MH  - Female
MH  - Heart Septal Defects, Ventricular/*surgery
MH  - Humans
MH  - Hypertension, Pulmonary/*surgery
MH  - Infant
MH  - Intensive Care Units/statistics & numerical data
MH  - Kaplan-Meier Estimate
MH  - Length of Stay/statistics & numerical data
MH  - Male
MH  - Preoperative Care
MH  - Pulmonary Artery/pathology/surgery
MH  - Retrospective Studies
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2010/06/10 06:00
MHDA- 2011/06/22 06:00
CRDT- 2010/06/10 06:00
PHST- 2010/06/10 06:00 [entrez]
PHST- 2010/06/10 06:00 [pubmed]
PHST- 2011/06/22 06:00 [medline]
AID - JCS1070 [pii]
AID - 10.1111/j.1540-8191.2010.01070.x [doi]
PST - ppublish
SO  - J Card Surg. 2010 Jul;25(4):400-5. doi: 10.1111/j.1540-8191.2010.01070.x. Epub 
      2010 May 30.