PMID- 20529156
OWN - NLM
STAT- MEDLINE
DCOM- 20110621
LR  - 20161125
IS  - 1540-8191 (Electronic)
IS  - 0886-0440 (Linking)
VI  - 25
IP  - 4
DP  - 2010 Jul
TI  - Left ventricle and left atrium remodeling after mitral valve replacement in case 
      of mixed mitral valve disease of rheumatic origin.
PG  - 367-72
LID - 10.1111/j.1540-8191.2010.01062.x [doi]
AB  - BACKGROUND: The objective of this study was to evaluate the recovery of the left 
      ventricle (LV) function, and to analyze postoperative size reduction of LV and 
      left atrium (LA), after mitral valve replacement (MVR) in patients with chronic 
      rheumatic mitral disease. METHODS: Thirty consecutive elective patients with MVR 
      for mixed mitral disease of rheumatic origin formed the study group. Of these, 21 
      (70%) were women and the mean age was 37 years. Transthoracic echocardiography 
      was performed prior to surgery, at three-month follow-up, and at three-year 
      follow-up except for the latest nine patients. RESULTS: The mean duration of 
      follow-up was 3.6 +/- 1.8 years. MVR surgery improved the functional class (mean 
      New York Heart Association [NYHA] class) at three-year follow-up (p = 0.008). LV 
      end-diastolic diameter and LA sizes decreased after MVR. Total chordal 
      preservation causes better outcome, regarding to LV ejection fraction (LVEF) and 
      NYHA functional class of patients. Preoperative high NYHA class, low LVEF, and 
      high LV end-systolic diameter (LVESd) resulted with postoperative LV dysfunction 
      (p were < 0.001, < 0.001, and 0.006, respectively). CONCLUSION: In patients with 
      mixed mitral valve disease, MVR enhanced LV and LA remodeling resulting in better 
      NYHA function. Preoperative NYHA, LVEF, and LVESd were significant predictors of 
      postoperative LV function.
FAU - Topal, Askin Ender
AU  - Topal AE
AD  - Cardiovascular Surgery Department, Medicine Faculty, Dicle University, 
      Diyarbakir, Turkey. aendertopal61@hotmail.com
FAU - Eren, Mehmet Nesimi
AU  - Eren MN
FAU - Celik, Yusuf
AU  - Celik Y
LA  - eng
PT  - Journal Article
DEP - 20100530
PL  - United States
TA  - J Card Surg
JT  - Journal of cardiac surgery
JID - 8908809
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Analysis of Variance
MH  - Cardiopulmonary Bypass/methods
MH  - Disease Progression
MH  - Echocardiography, Transesophageal
MH  - Female
MH  - Health Status Indicators
MH  - Heart Atria/*pathology/surgery
MH  - Heart Valve Prosthesis Implantation/*methods
MH  - Heart Ventricles/*pathology/surgery
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve Insufficiency/diagnostic imaging/*pathology/surgery
MH  - Postoperative Complications
MH  - Prospective Studies
MH  - Rheumatic Heart Disease/*pathology/surgery
MH  - Stroke Volume
MH  - Ventricular Function, Left
MH  - *Ventricular Remodeling
MH  - Young Adult
EDAT- 2010/06/10 06:00
MHDA- 2011/06/22 06:00
CRDT- 2010/06/10 06:00
PHST- 2010/06/10 06:00 [entrez]
PHST- 2010/06/10 06:00 [pubmed]
PHST- 2011/06/22 06:00 [medline]
AID - JCS1062 [pii]
AID - 10.1111/j.1540-8191.2010.01062.x [doi]
PST - ppublish
SO  - J Card Surg. 2010 Jul;25(4):367-72. doi: 10.1111/j.1540-8191.2010.01062.x. Epub 
      2010 May 30.