PMID- 20536519
OWN - NLM
STAT- MEDLINE
DCOM- 20101018
LR  - 20191210
IS  - 1464-5491 (Electronic)
IS  - 0742-3071 (Linking)
VI  - 27
IP  - 4
DP  - 2010 Apr
TI  - Implementation and effectiveness of the first community lifestyle intervention 
      programme to prevent Type 2 diabetes in Greece. The DE-PLAN study.
PG  - 459-65
LID - 10.1111/j.1464-5491.2010.02918.x [doi]
AB  - AIMS: To report our experience of implementing the first community-based 
      lifestyle intervention programme to detect high-risk individuals and prevent the 
      development of Type 2 diabetes mellitus (T2DM) in a general population sample in 
      Athens, Greece (the DE-PLAN Study). METHODS: The Finnish Type 2 Diabetes Risk 
      Score (FINDRISC) questionnaire was distributed to 7900 people at workplaces and 
      primary-care centres. High-risk individuals were invited to receive an oral 
      glucose tolerance test (OGTT) and, after excluding persons with diabetes, to 
      participate in a 1-year intervention programme, based on bimonthly sessions with 
      a dietitian. RESULTS: Three thousand, two hundred and forty questionnaires were 
      returned; 620 high-risk individuals were identified and 191 agreed to 
      participate. Recruitment from workplaces was the most successful strategy for 
      identifying high-risk persons, enrolling and maintaining them throughout the 
      study. The 125 participants who fully completed the programme (66 did not return 
      for a second OGTT) lost on average 1.0+/-4.7 kg (P=0.022). Higher adherence to 
      the intervention sessions resulted in more significant weight loss (1.1+/-4.8 vs. 
      0.6+/-4.6 kg for low adherence). Persons with impaired fasting glucose (IFG) 
      and/or impaired glucose tolerance (IGT) at baseline lost more weight than those 
      with normal glucose tolerance (1.5+/-4.8 vs. -0.2+/-4.5 kg). The percentage of 
      people with any type of dysglycaemia (IFG/IGT) was lower after the intervention 
      (68.0% at baseline vs. 53.6% 1 year later, P=0.009); 5.6% developed diabetes. 
      CONCLUSIONS: The implementation of a lifestyle intervention programme to prevent 
      T2DM in the community is practical and feasible, accompanied by favourable 
      lifestyle changes. Recruitment from workplaces was the most successful strategy.
FAU - Makrilakis, K
AU  - Makrilakis K
AD  - First Department of Propaedeutic Medicine, Athens University Medical School, 
      Laiko General Hospital, Athens, Greece. kmakrila@med.uoa.gr
FAU - Liatis, S
AU  - Liatis S
FAU - Grammatikou, S
AU  - Grammatikou S
FAU - Perrea, D
AU  - Perrea D
FAU - Katsilambros, N
AU  - Katsilambros N
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Diabet Med
JT  - Diabetic medicine : a journal of the British Diabetic Association
JID - 8500858
SB  - IM
MH  - Adult
MH  - Aged
MH  - Community Health Services/*organization & administration
MH  - Diabetes Mellitus, Type 2/diagnosis/*prevention & control
MH  - Diet
MH  - Exercise
MH  - Female
MH  - Greece
MH  - Humans
MH  - *Life Style
MH  - Male
MH  - Middle Aged
MH  - Patient Compliance
MH  - Patient Education as Topic/*methods
MH  - Primary Health Care
MH  - *Program Development
MH  - Program Evaluation
MH  - Surveys and Questionnaires
MH  - Weight Loss
MH  - Workplace
EDAT- 2010/06/12 06:00
MHDA- 2010/10/19 06:00
CRDT- 2010/06/12 06:00
PHST- 2010/06/12 06:00 [entrez]
PHST- 2010/06/12 06:00 [pubmed]
PHST- 2010/10/19 06:00 [medline]
AID - DME2918 [pii]
AID - 10.1111/j.1464-5491.2010.02918.x [doi]
PST - ppublish
SO  - Diabet Med. 2010 Apr;27(4):459-65. doi: 10.1111/j.1464-5491.2010.02918.x.