PMID- 20536653
OWN - NLM
STAT- MEDLINE
DCOM- 20101004
LR  - 20151119
IS  - 1346-8138 (Electronic)
IS  - 0385-2407 (Linking)
VI  - 37
IP  - 5
DP  - 2010 May
TI  - Sarcoidosis during infliximab therapy for Crohn's disease.
PG  - 471-4
LID - 10.1111/j.1346-8138.2010.00861.x [doi]
AB  - Tumor necrosis factor-alpha (TNF-alpha) antagonists are effective for 
      inflammatory diseases, such as Crohn's disease, rheumatoid arthritis (RA) and 
      psoriasis. Although TNF-alpha antagonists are also useful for sarcoidosis, 
      paradoxical occurrence of sarcoidosis or sarcoidal reaction may be observed. We 
      report a Crohn's disease patient, who developed sarcoidosis during infliximab 
      therapy. A 35-year-old man had been receiving infliximab for 7 months for Crohn's 
      disease. He developed cough and fever, accompanied by an infiltrated erythematous 
      plaque on his right knee. The chest radiography, skin biopsy and laboratory 
      findings were all consistent with sarcoidosis.
FAU - Takahashi, Hidetoshi
AU  - Takahashi H
AD  - Department of Dermatology, Asahikawa Medical College, Asahikawa, Japan. 
      hidetaka@psy.med.osaka-u.ac.jp
FAU - Kaneta, Kazuhiro
AU  - Kaneta K
FAU - Honma, Masaru
AU  - Honma M
FAU - Ishida-Yamamoto, Akemi
AU  - Ishida-Yamamoto A
FAU - Ashida, Tomonori
AU  - Ashida T
FAU - Kohgo, Yutaka
AU  - Kohgo Y
FAU - Ohsaki, Yoshinobu
AU  - Ohsaki Y
FAU - Iizuka, Hajime
AU  - Iizuka H
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - J Dermatol
JT  - The Journal of dermatology
JID - 7600545
RN  - 0 (Anti-Inflammatory Agents)
RN  - 0 (Antibodies, Monoclonal)
RN  - 0 (Tumor Necrosis Factor-alpha)
RN  - B72HH48FLU (Infliximab)
SB  - IM
MH  - Adult
MH  - Anti-Inflammatory Agents/*adverse effects
MH  - Antibodies, Monoclonal/*adverse effects
MH  - Crohn Disease/*drug therapy
MH  - Humans
MH  - Infliximab
MH  - Knee/*pathology
MH  - Male
MH  - Sarcoidosis/*chemically induced/diagnosis
MH  - Treatment Outcome
MH  - Tumor Necrosis Factor-alpha/antagonists & inhibitors
EDAT- 2010/06/12 06:00
MHDA- 2010/10/05 06:00
CRDT- 2010/06/12 06:00
PHST- 2010/06/12 06:00 [entrez]
PHST- 2010/06/12 06:00 [pubmed]
PHST- 2010/10/05 06:00 [medline]
AID - JDE861 [pii]
AID - 10.1111/j.1346-8138.2010.00861.x [doi]
PST - ppublish
SO  - J Dermatol. 2010 May;37(5):471-4. doi: 10.1111/j.1346-8138.2010.00861.x.