PMID- 20537280
OWN - NLM
STAT- MEDLINE
DCOM- 20101115
LR  - 20151119
IS  - 1945-8932 (Electronic)
IS  - 1945-8932 (Linking)
VI  - 24
IP  - 3
DP  - 2010 May-Jun
TI  - Outcomes after endoscopic sinus surgery for unilateral versus bilateral chronic 
      rhinosinusitis with nasal polyposis.
PG  - 83-6
LID - 10.2500/ajra.2010.24.3482 [doi]
AB  - BACKGROUND: Endoscopic sinus surgery (ESS) is a safe and reliable procedure for 
      the treatment of chronic rhinosinusitis (CRS) and nasal polyposis (NP). Although 
      most cases of CRS with NP occur bilaterally, we occasionally encounter patients 
      with unilateral sinus disease with NP. Because no study has been conducted on the 
      surgical outcomes between unilateral and bilateral CRS with NP after ESS, we 
      evaluated subjective and objective outcomes between patients with unilateral and 
      bilateral CRS with NP. METHODS: A total of 181 patients diagnosed with CRS with 
      NP were enrolled. Twenty-three patients had unilateral CRS with NP and 158 
      patients had bilateral disease. The extent of NP, Lund-Mackay score, and involved 
      sinuses were evaluated with nasal endoscopy and preoperative computed tomography 
      (CT). Objective and subjective surgical outcomes were assessed 6 months after 
      ESS, using endoscopic findings, the Sino-Nasal Outcome Test 20 (SNOT-20), and 
      visual analog scales. RESULTS: The extent of NP and Lund-Mackay score did not 
      differ significantly between the two groups. The SNOT-20 and six main symptom 
      scores included in the questionnaire were significantly improved 6 months 
      postoperatively in both groups, with no significant difference between the 
      groups. However, the unilateral group showed significantly better objective 
      outcomes than the bilateral group. CONCLUSION: Unilateral CRS with NP showed more 
      favorable objective surgical outcomes than bilateral disease. We suggest that the 
      developmental mechanisms of the two disease entities may be different and that 
      bilateral CRS with NP may be more intimately associated with a patient's innate 
      tendency to develop NP.
FAU - Lee, Jae Yong
AU  - Lee JY
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang 
      University, College of Medicine, Bucheon Hospital, Bucheon, South Korea. 
      jyent@schbc.ac.kr
FAU - Byun, Jang Yul
AU  - Byun JY
FAU - Shim, Sung Shine
AU  - Shim SS
FAU - Lee, Seung Won
AU  - Lee SW
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Am J Rhinol Allergy
JT  - American journal of rhinology & allergy
JID - 101490775
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Chronic Disease
MH  - *Endoscopy
MH  - Follow-Up Studies
MH  - Humans
MH  - Middle Aged
MH  - Nasal Obstruction
MH  - Nasal Polyps
MH  - Paranasal Sinuses/pathology/surgery
MH  - Rhinitis/*diagnosis/pathology/physiopathology/*surgery
MH  - Sinusitis/*diagnosis/pathology/physiopathology/*surgery
MH  - Surveys and Questionnaires
MH  - Tomography, X-Ray Computed
MH  - Treatment Outcome
EDAT- 2010/06/12 06:00
MHDA- 2010/11/16 06:00
CRDT- 2010/06/12 06:00
PHST- 2010/06/12 06:00 [entrez]
PHST- 2010/06/12 06:00 [pubmed]
PHST- 2010/11/16 06:00 [medline]
AID - 10.2500/ajra.2010.24.3482 [doi]
PST - ppublish
SO  - Am J Rhinol Allergy. 2010 May-Jun;24(3):83-6. doi: 10.2500/ajra.2010.24.3482.