PMID- 20541587
OWN - NLM
STAT- MEDLINE
DCOM- 20101019
LR  - 20100713
IS  - 1872-8324 (Electronic)
IS  - 0303-2647 (Linking)
VI  - 101
IP  - 2
DP  - 2010 Aug
TI  - A power-law distribution of inter-spike intervals in renal sympathetic nerve 
      activity in salt-sensitive hypertension-induced chronic heart failure.
PG  - 144-7
LID - 10.1016/j.biosystems.2010.06.002 [doi]
AB  - To assess sympathetic variability in chronic heart failure (CHF), we evaluated a 
      distribution of inter-spike intervals (ISIs) in renal sympathetic nerve activity 
      (RSNA) in salt-sensitive hypertension-induced CHF (DSSH-CHF) rats. Dahl 
      salt-sensitive rats were fed an 8% NaCl diet for 9 weeks to induce salt-sensitive 
      hypertension-induced CHF. ISIs in RSNA were obtained from chronically 
      instrumented conscious rats, and counts (frequency) and ranks of ISIs in RSNA 
      were plotted with a histogram. We found that ISIs in RSNA followed a power-law 
      distribution in rats, and the power-law distribution of ISIs for RSNA in DSSH-CHF 
      rats was significantly different from that in normal rats. These results 
      indicated that sympathetic variability may be significantly different between 
      salt-sensitive hypertension-induced CHF and healthy individuals, which suggests 
      that sympathetic variability may be used to predict abnormality of the 
      sympathetic regulatory system.
FAU - Kemuriyama, Takehito
AU  - Kemuriyama T
AD  - Department of Physiology, National Defense Medical College, Tokorozawa, Saitama, 
      Japan. kemu@ndmc.ac.jp
FAU - Ohta, Hiroyuki
AU  - Ohta H
FAU - Sato, Yoshiaki
AU  - Sato Y
FAU - Maruyama, Satoshi
AU  - Maruyama S
FAU - Tandai-Hiruma, Megumi
AU  - Tandai-Hiruma M
FAU - Kato, Kazuo
AU  - Kato K
FAU - Nishida, Yasuhiro
AU  - Nishida Y
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20100610
PL  - Ireland
TA  - Biosystems
JT  - Bio Systems
JID - 0430773
SB  - IM
MH  - Action Potentials/*physiology
MH  - Animals
MH  - Electrocardiography
MH  - Heart Failure/*etiology/*physiopathology
MH  - Hypertension/*complications
MH  - Kidney/*innervation
MH  - Rats
MH  - Rats, Inbred Dahl
MH  - Rats, Sprague-Dawley
MH  - Regression Analysis
MH  - Species Specificity
MH  - Sympathetic Nervous System/*physiology
EDAT- 2010/06/15 06:00
MHDA- 2010/10/20 06:00
CRDT- 2010/06/15 06:00
PHST- 2010/03/15 00:00 [received]
PHST- 2010/06/03 00:00 [revised]
PHST- 2010/06/04 00:00 [accepted]
PHST- 2010/06/15 06:00 [entrez]
PHST- 2010/06/15 06:00 [pubmed]
PHST- 2010/10/20 06:00 [medline]
AID - S0303-2647(10)00097-3 [pii]
AID - 10.1016/j.biosystems.2010.06.002 [doi]
PST - ppublish
SO  - Biosystems. 2010 Aug;101(2):144-7. doi: 10.1016/j.biosystems.2010.06.002. Epub 
      2010 Jun 10.