PMID- 20546002 OWN - NLM STAT- MEDLINE DCOM- 20110325 LR - 20161125 IS - 1540-8175 (Electronic) IS - 0742-2822 (Linking) VI - 27 IP - 7 DP - 2010 Aug TI - Immediate and follow-up results of repeat percutaneous mitral balloon commissurotomy for restenosis after a succesful first procedure. PG - 765-9 LID - 10.1111/j.1540-8175.2010.01150.x [doi] AB - BACKGROUND: The widespread use of percutaneous mitral commissurotomy (PMC) has led to an increase in restenosis cases. The data regarding follow-up results of repeat PMC are quite limited. The aim of this retrospective analysis is to evaluate the immediate and midterm results of the second PMC, in patients with symptomatic mitral restenosis after a succesful first procedure. METHODS: Twenty patients (95% female, mean age 37 +/- 4 years) who have undergone a second PMC, 6.3 +/- 2.5 years after a first successful intervention built the study group. All were in sinus rhythm, with a mean Wilkins score of 8.5 +/- 1.2. RESULTS: The valve area increased from 1.2 +/- 0.2 to 1.9 +/- 0.2 cm(2) and mean gradient decreased from 10.5 +/- 3.4 to 6.1 +/- 1.1 mmHg. There were no complications except for a transient embolic event without sequela (5%) and two cases (10%) of severe mitral regurgitation. The immediate success rate was 90%. The mean follow-up was 70 +/- 29 months (36-156 months). The 5-year restenosis and intervention (repeat PMC or valve replacement) rates were 9.1 +/- 5.2% and 3.6 +/- 3.3%, respectively. The intervention free 5-year survival in good functional capacity (New York Heart Association [NYHA] I-II) was 95.1 +/- 5.5% and restenosis and intervention free 5-year survival with good functional capacity was 89.7 +/- 6.8%. CONCLUSIONS: Although from a limited number of selected patients, these findings indicate that repeat PMC is a safe and effective method, with follow-up results similar to a first intervention and should be considered as the first therapeutic option in suitable patients. CI - (c) 2010, Wiley Periodicals, Inc. FAU - Yazicioglu, Nuran AU - Yazicioglu N AD - Department of Cardiology, Institute of Cardiology, Istanbul University, Istanbul, Turkey. FAU - Arat Ozkan, Alev AU - Arat Ozkan A FAU - Orta Kilickesmez, Kadriye AU - Orta Kilickesmez K FAU - Celiker, Cengiz AU - Celiker C FAU - Mert, Murat AU - Mert M FAU - Pehlivanoglu, Seckin AU - Pehlivanoglu S FAU - Enar, Rasim AU - Enar R FAU - Karatay, Canan AU - Karatay C FAU - Kucukoglu, Serdar AU - Kucukoglu S LA - eng PT - Journal Article PL - United States TA - Echocardiography JT - Echocardiography (Mount Kisco, N.Y.) JID - 8511187 SB - IM MH - Adult MH - Angioplasty, Balloon/*statistics & numerical data MH - Female MH - Follow-Up Studies MH - Humans MH - Incidence MH - Male MH - Middle Aged MH - Mitral Valve Stenosis/diagnostic imaging/*epidemiology/*therapy MH - Reoperation/statistics & numerical data MH - Risk Assessment MH - Risk Factors MH - Treatment Outcome MH - Turkey MH - Ultrasonography EDAT- 2010/06/16 06:00 MHDA- 2011/03/26 06:00 CRDT- 2010/06/16 06:00 PHST- 2010/06/16 06:00 [entrez] PHST- 2010/06/16 06:00 [pubmed] PHST- 2011/03/26 06:00 [medline] AID - ECHO1150 [pii] AID - 10.1111/j.1540-8175.2010.01150.x [doi] PST - ppublish SO - Echocardiography. 2010 Aug;27(7):765-9. doi: 10.1111/j.1540-8175.2010.01150.x.