PMID- 20554094
OWN - NLM
STAT- MEDLINE
DCOM- 20110324
LR  - 20151119
IS  - 1532-1983 (Electronic)
IS  - 0261-5614 (Linking)
VI  - 29
IP  - 6
DP  - 2010 Dec
TI  - C-reactive protein levels are associated with adiposity and a high inflammatory 
      foods index in mountainous Cypriot children.
PG  - 779-83
LID - 10.1016/j.clnu.2010.05.001 [doi]
AB  - BACKGROUND & AIMS: Inflammatory marker levels have long been associated with 
      obesity status in adult populations, but relevant data are scarce in children, 
      especially in diverse races. The aim of this study was thus to examine the 
      association between overall and central obesity and C-reactive protein (CRP) 
      levels in Cypriot children of Greek ancestry. METHODS: Eighty three children (9.2 
      +/- 1.7 years) were studied. Body mass index (BMI) was calculated according to the 
      age-sex specific International Obesity Task Force (IOTF) criteria while body fat 
      percentage (BF%) was measured via leg-to-leg bioelectric impedance (BIA). Central 
      obesity was defined as waist circumference >/= 75 th percentile. Physical activity 
      was assessed using a pedometer and diet quality was evaluated by applying the 
      KIDMED index. An inflammatory foods' index, composed of nine foods/food groups, 
      was also calculated. CRP levels were measured using a high-sensitivity (hs) 
      immunoassay. RESULTS: Obese children, children with excess BF% and children with 
      WC >/= 75 th percentile were 7.35, 6.84 and 7.81 times (P < 0.05) respectively more 
      likely to have hs-CRP levels >/= 0.10 mg/dL; a high score of the dietary 
      inflammation index was positively associated with CRP levels. CONCLUSIONS: 
      Obesity is associated with increased hs-CRP levels in 6-12 year-old children, a 
      finding that supports the inflammation-obesity hypothesis at an early stage of 
      life. Furthermore, frequent consumption of inflammatory foods is positively 
      related to CRP levels.
CI  - Copyright (c) 2010 Elsevier Ltd and European Society for Clinical Nutrition and 
      Metabolism. All rights reserved.
FAU - Lazarou, Chrystalleni
AU  - Lazarou C
AD  - Department of Dietetics and Nutrition, Harokopio University, Athens, Greece. 
      stalolaz@logosnet.cy.net
FAU - Panagiotakos, Demosthenes B
AU  - Panagiotakos DB
FAU - Chrysohoou, Christina
AU  - Chrysohoou C
FAU - Andronikou, Chrysostomos
AU  - Andronikou C
FAU - Matalas, Antonia-Leda
AU  - Matalas AL
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Clin Nutr
JT  - Clinical nutrition (Edinburgh, Scotland)
JID - 8309603
RN  - 0 (Biomarkers)
RN  - 9007-41-4 (C-Reactive Protein)
SB  - IM
MH  - *Adiposity
MH  - Atherosclerosis/metabolism
MH  - Biomarkers/analysis
MH  - Body Mass Index
MH  - C-Reactive Protein/*analysis
MH  - Child
MH  - Child Nutritional Physiological Phenomena
MH  - Cross-Sectional Studies
MH  - Cyprus/epidemiology
MH  - *Diet
MH  - Female
MH  - Humans
MH  - Immunoassay
MH  - Inflammation/*metabolism
MH  - Male
MH  - Obesity, Abdominal/*metabolism
MH  - Risk Factors
MH  - Waist Circumference
EDAT- 2010/06/18 06:00
MHDA- 2011/03/25 06:00
CRDT- 2010/06/18 06:00
PHST- 2010/02/11 00:00 [received]
PHST- 2010/04/27 00:00 [revised]
PHST- 2010/05/01 00:00 [accepted]
PHST- 2010/06/18 06:00 [entrez]
PHST- 2010/06/18 06:00 [pubmed]
PHST- 2011/03/25 06:00 [medline]
AID - S0261-5614(10)00086-5 [pii]
AID - 10.1016/j.clnu.2010.05.001 [doi]
PST - ppublish
SO  - Clin Nutr. 2010 Dec;29(6):779-83. doi: 10.1016/j.clnu.2010.05.001.